Abstract：Objective To evaluate the effectiveness of two Methods for lagophthalmus induced by thyroid-associated ophthalmopathy, so as to prevent some complications of ocular surface such as conjunctival hyperemia, dry eye, tears, exposure keratopathy. Methods 160 patients diagnosed as having thyroid-associated ophthalmopathy with lagophthalmus were randomly divided into two groups. In the study group, the affected eyes were protected by transparent medical film(3M Tegaderm),as well as treated by tobramycin eye drops and erythromycin eye ointment. In the control group, the affected eyes were just protected by tobramycin eye drops and erythromycin eye ointment in the same duration. The improvement of the corneal epithelium defect and other complications of ocular surface in the two groups were observed and compared. Results After 72 hours, the conditions of the corneal epithelium defect improved in 95.8% of eyes in the study group as well as in 61.0% of eyes in the control group, The Results had statistically significant difference between the two groups(P<0.05). Eye symptoms of discomfort occurred in 34 eyes (23.6%) in the study group as well as in 104 eyes (70.3%) in the control group. The Results had statistically significant difference between the two groups (P<0.01). Conclusions The appropriate application of transparent medical film combined with antibiotic eye drops and eye ointment can relieve the patient’s eye symptoms of discomfort and reduce the incidence of complications. It is an ideal and easy way to treat this aliment.
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2014, Vol. 25 
