Abstract:Objective To study the acute kidney injury and immunoglobulins changes in the hepatocellulor carcinoma patients who underwent contrast-enhanced CT (CECT) examination. Methods A total of 54 patients(34 primary hepatic carcinoma patients and 20 hepatic hemangioma patients) were included in this study who underwent CECT examination. The individual information was collected from each patient. Then we examined the level of SG,pH and MAU in urine, and the level of BUN,Scr,β2MG,Cysc,CRP,IgA,IgG and IgM in serum before and after 24 hours CECT examination respectively. Results After CECT examination, all the patients’ level of pH,MAU and the primary hepatic carcinoma patients’ level of β2MG were much higher than those of before, while the IgM level of all the patients reduced significantly, the difference was statistically significant (P<0.05). However, the changes in SG,BUN,Scr,Cysc,CRP,IgA and IgG had no significant difference. Conclusions Contrast media may lead renal function and immune system damage to the hepatocellulor carcinoma patients who undergo CECT.
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Ledermann H P, Mengiardi B, Schmid A, et al. Screening for renal insufficiency following ESUR (European Society of Urogenital Radiology) guidelines with on-site creatinine measurements in an outpatient setting[J].Eur Radiol, 2010,20(8):1926-1933.