Abstract：Objective To investigate the efficacy and safety of endoscopic mask for painless gastroscopy examination in obese patients. Methods 100 patients with body mass index (BMI) ＞28 kg/m2 who received painless gastroscopy examination were randomized into two groups. Patients in group T inhaled oxygen with endoscopic mask(n=50), and patients in group C inhaled oxygen with nasal cannula(n=50).In the two groups, oxygen flow rates were set at 3-5 L/min.All patients were intravenously injected fentanyl 0.05 mg, midazolam 1 mg, and followed by propofol 1-2 mg/kg. Physicians began to examine when patients lost consciousness. During the procedure, propofol was given in time to keep a level of deep sedation if the patients had small body movement. SBP, DBP, HR, SpO2 of T1 (before anesthesia), T2 (two minutes after anesthesia), T3 (at the end of examination) were recorded. In addition, the examination time, total dose of propofol administration in the two groups were recorded. Results (1) Compared with T1, the SBP、DBP and HR in the two groups at T1, T2 decreased distinctly, the differences were statistically significant (P<0.05). (2) At T2, the SpO2 in group C decreased significantly, there were 6 patients(12％) with SPO2<90％, compared with T1, the difference was statistically significant(P<0.05); the SpO2 in group T increased, which was statistically significant. At T2, the SpO2 (99.26%±0.90%) in group T significantly higher than that in group C (92.68%±2.30%), the difference was statistically significant (P<0.05). At T3, there was also significant difference between the two groups [(99.58%±0.61%) vs (96.24%±0.98%)].(3) Compared with the examination time and total dose of propofol of the two groups, the differences were not statistically significant. Conclusions The application of oxygen inhalation with endoscopic mask appears to be more safer than that of oxygen inhalation with nasal cannula for painless gastroscopy examination in obese patients.
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Faigel D O, Baron T H, Goldstein J L, et al. Guidelines for the use of deep sedation and general anesthesia for GI endoscopy[J]. Gastrointest Endosc, 2002, 56(5):613-617.
2015, Vol. 26 
