Research of bone mineral density in renal transplantation recipients
CAO Yong1,2, WANG Hongyu1, NIU Yujian3, ZHANG Shaofeng1, XU Chun1
1.Department of Endocrinology, 3.Organ Transplantation Institute, The General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China; 2.Graduate School of Xuzhou Medical College, Xuzhou 221004, China
Abstract：Objective To study the differences in bone mineral density (BMD) and incidence of bone loss (osteopenia and osteoporosis). Methods Todally 177 renal transplantation recipients (104 males, 73 females) were divided into postmenopausal women, premenopausal women and ＜50-year-old males and ≥50-year-old males. And 250 people with normal physical examination (131 males, 119 females) were included in control group. Bone mineral densities of the lumbar spine, right femoral neck and right hip were assessed by dual X-ray absorptiometry. The transplantation group and the control group were compared in the BMD and incidence of bone loss. Results BMDs of right femoral neck and right hip in all transplantation group were significantly lower than those in the control group (P<0.01).BMD of the lumbar spine in transplantation group of ＜50-year-old males was significantly lower than that in the control group(P<0.01).The incidences of bone loss in males and postmenopausal women were significantly higher than those in the control group(P<0.01). Conclusions BMD in renal transplantation recipients is lower than in normal physical examination. The prevalence of bone loss in renal transplantation recipients is significantly higher than that in normal people. It is suggested that we should on the basis of vitamin and calcium ,select diphosphonate to prevent and treat osteoporosis and bone fracture after renal transplantation.
曹永, 王宏宇, 牛玉坚, 张韶峰, 徐春. 肾移植术后患者骨密度水平的调查研究[J]. 武警医学, 2015, 26(8): 780-782.
CAO Yong, WANG Hongyu, NIU Yujian, ZHANG Shaofeng, XU Chun. Research of bone mineral density in renal transplantation recipients. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(8): 780-782.
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2015, Vol. 26 
