Relationship between thyroid nodule calcification and thyroid cancer
LIU Langbiao1,HAN Chengxin2, SHU Qingming3,XU Xin3, and JIA Yuanli2
1.Department of General Surgery, Beijing Tongzhou Xinhua Hospital, Beijing 101100, China; 2. Department of General Surgery, 3. Department of Pathology, General Hospital of Chinese People’s Armed Police Force, Beijing 100039, China
Abstract:Objective To evaluate the relationship between sonographic patterns of thyroid nodule calcification and thyroid cancer.Methods Fifty-eight patients who had undergone thyroid surgery in the General Hospital of Chinese People’s Armed Police Force between June 2012 and August 2012 were retrospectively analyzed, with emphasis on benign and malignant thyroid nodular calcification in general and preoperative ultrasound examination of thyroid nodule calcification, postoperative pathologic Results, and the relationships between preoperative ultrasonographic calcification and thyroid cancer in particular.Results Among the 58 cases, there were 31 cases of benign lesions and 27 cases of thyroid papillary carcinoma. The detection rate of preoperative ultrasound calcification was 39.7%, the pathological calcification rate was 38%, and intraoperative frozen calcification rate was 17.2%. The detection rate of benign calcification was 16.1%, the incidence of microcalcification of benign lesions was 6.4%, the incidence of calcification of thyroid papillary carcinoma was 66.7%, and the incidence of microcalcification was 51.9%.The differences of microcalcification between benign lesions and malignant lesions were statistically significant (P<0.01). The calcification incidence of the single benign nodular was 20%, and the calcification incidence of the single malignant nodular was 61.1%, so where was significant difference between them (P<0.01).Conclusion Thyroid nodule microcalcification detected by ultrasound is closely related to thyroid cancer.
Consorti F, Anello A, Benvenuti C, et al. Clinical Value of calcifications in thyroid carcinoma and multinodular goiter[J]. Anticancer Res,2003,23(3C):3089-3092.
[4]
Takis S, Terahats S,Yamashita R,et al. Thyroid calcifications:sonographic patterns and incidence of cancer[J].Clin Imaging,2004,28(5):368-371.