结核性与肿瘤性腹膜弥漫性病变的<sup>18</sup>F-FDG PET/CT影像特征比较

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摘要目的探讨结核性与肿瘤性腹膜弥漫性病变的¹⁸F-FDG PET/CT相关影像表现。方法对结核性与肿瘤性腹膜弥漫性病变的相关¹⁸F-FDG PET/CT影像表现进行量化分级,采用χ²检验、两样本独立t检验、Logistic回归及ROC曲线进行统计学分析。结果单因素分析结果显示,腹膜SUVmax、腹水CT值、壁腹膜增厚情况、网膜增厚情况及其他脏器受累情况在结核性与肿瘤性腹膜弥漫性病变中差异有统计学意义(P<0.05);多因素分析显示,网膜增厚情况及其他脏器受累情况在结核性与肿瘤性腹膜弥漫性病变中差异有统计学意义(P<0.05),二元Logistic回归方程为Y=1.201+1.517X3+1.980X9,X3及X9的OR值分别为4.559(95% CI:0.707~29.391)及7.242(95% CI:1.726~30.385);ROC曲线显示网膜增厚情况、其他脏器受累情况对结核性及肿瘤性病变的鉴别有效,两者的AUC分别是0.670(95% CI:0.527～0.813)和0.655(95% CI:0.525～0.785),前者的诊断效能较高(P<0.05)。结论分析结核性与肿瘤性腹膜弥漫性病变的¹⁸F-FDG PET/CT影像表现,可提高两者的鉴别诊断水平。

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	尹亮
	黄世明
	林志春
	岳建兰
	陈薇

关键词 ：腹膜弥漫性病变, 体层摄影术, 发射型计算机, 体层摄影术, X线计算机, 脱氧葡萄糖

Abstract：Objective To analyze the difference of ¹⁸F-FDG PET/CT imaging features between tuberculous and cancerous diffuse peritoneal lesions.Methods Quantitative classification of ¹⁸F-FDG PET/CT imaging features of tuberculous and cancerous diffuse peritoneal lesions was conducted. Statistical methods, such as analysis of variance, chi-square test, two independent sample t-test and cumulative logistic model were applied to analysis of the data.Results Single factor statistical analysis showed that there was statistically significant difference (P<0.05) in the involvement of peritoneal SUVmax, ascites CT value, thickening of parietal peritoneum and omentum, and other organs in tuberculous and cancerous diffuse peritoneal lesions. Multivariable statistical analysis showed that there was statistically significant difference (P<0.05) in the involvement of omentum thickening and other organs in tuberculous and cancerous diffuse peritoneal lesions. The binary logistic regression analysis equation was Y=1.201+1.517X3+1.980X9,and the odds ratio of X3 and X9 was 4.559 (95% CI:0.707-29.391) and 7.242(95% CI:1.726-30.385), respectively. The ROC curve showed that the degree of involvement of omentum thickening and other organs could help identify tuberculous and tumor lesions effectively. The AUC (area under curve) of omentum thickening was 0.670 (95% CI: 0.527-0.813), which was better than that of other organs involved (0.655, 95% CI:0.525-0.785).Conclusion The level of differential diagnosis can benefit from careful analysis of ¹⁸F-FDG PET/CT imaging features of tuberculous and cancerous diffuse peritoneal lesions.

Key words： diffuse peritoneal lesions tomography, emission-computer tomography, X-ray computer deoxyglucose

收稿日期: 2016-09-05

ZTFLH:

R445.2

基金资助:天津市应用基础及前沿技术研究计划(13JCYBJC22000)

通讯作者: 林志春,E-mail: zhichunlin@163.com

作者简介: 尹亮,硕士,医师。

引用本文:

尹亮,黄世明,林志春,岳建兰,陈薇. 结核性与肿瘤性腹膜弥漫性病变的¹⁸F-FDG PET/CT影像特征比较[J]. 武警医学, 2017, 28(2): 182-185. YIN Liang, HUANG Shiming, LIN Zhichun, YUE Jianlan, and CHEN Wei. Features of ¹⁸F-FDG PET/CT imaging in differential diagnosis of tuberculous and cancerous diffuse peritoneal lesions. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(2): 182-185.

链接本文:

http://journal08.magtechjournal.com/Jwk_wjyx/CN/ 或 http://journal08.magtechjournal.com/Jwk_wjyx/CN/Y2017/V28/I2/182

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