Abstract：Objective To investigate the short-term effect of laparoscopy-assisted distal gastrectomy(LADG)for elder gastric cancer patients at the progressive stage.Methods One hundred and twenty-eight patients with gastric cancer who had undergone LADG and another 128 patients treated with traditional open abdominal surgery were compared in terms of intraoperative and postoperative indexes, leukocyte count, C reactive protein, plasma motilin, vasoactive intestinal peptide and somatostatin.Results The amount of intraoperative bleeding, size of surgical incision, and the first anus exhaust time in the laparoscopy group were significantly smaller or earlier than those in the laparotomy group(P<0.05). WBC and CRP values of the two groups changed with time (P<0.05), and were significantly lower in the laparoscopic group than in the laparotomy group (P<0.05) at different stages. The interactions between different surgical methods and time had effect on the values of WBC and CRP (P<0.05). The plasma motilin, vasoactive intestinal peptide and somatostatin in the two groups changed with time (P<0.05). The values of plasma motilin in the laparoscopic group were significantly higher than those in the laparotomy group at different stages, while the values of vasoactive intestinal peptide and somatostatin were significantly lower (P<0.05). The interactions between surgical approaches and time had some effect on plasma motilin, vasoactive intestinal peptide and somatostatin (P<0.05). There was no significant difference in complications between the two groups, P>0.05.Conclusions LADG has obvious advantages in reducing the amount of bleeding, surgical incision, hospital stay and inflammatory responses, and in promoting the recovery of gastrointestinal function.
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2019, Vol. 30 
