Effect of early mobilities on safety in ICU patients with continuous renal replacement therapy
ZHAO Hongyu1, TANG Sheng2, MA Yanlan3, LUO Sha4, LI Lina5, CAO Yurui1, YANG Ning1
1. Medical School of Chinese PLA,Beijing 100853,China; 2. Department of SICU,4. Department of KICU, 5. Department of RICU, the First Medical Centre of Chinese PLA General Hospital,Beijing 100853; 3. Department of Medical Training Center,Chinese PLA General Hospital,Beijing 100853,China
Abstract：Objective To investigate the effect of early mobilities on the safety in ICU patients with continuous renal replacement therapy (CRRT). Methods Eighteen patients with CRRT were randomly divided into experimental group (n=9) and control group (n=9) by computer random number table method. The control group was given routine treatment and nursing, while the experimental group performed active and passive range of motion during CRRT on-machine.The CRRT pressure parameters (arterial pressure PA, venous pressure PV, prefiltration pressure PBE, and Transmembrane pressure TMP) and vital signs (blood pressure BP, heart rate HR, respiratory rate RR, blood oxygen saturation SpO2) were compared before (0 min), during (15 min) and after (30 min) the mobility, and the occurrence of adverse events in the two groups were also compared. Results All the patients completed the study, and the experimental group completed 41 times of early mobilities, while the control group were recorded 36 times. There was no significant difference in CRRT pressure parameters between the two groups at different time points (0, 15, 30 min) (P>0.05). There was statistically significant difference in PA at 30 min[(-80.41±31.91)mmHg] and at 0 min[(-76.54±33.59)mmHg] in the experimental group (P=0.005); PV at 15 min [(57.05±20.99)mmHg] and at 0 min[(54.80±22.82)mmHg], the difference was statistically significant (P=0.024); the PV at 30 min [(59.85±21.73)mmHg] was significantly different from that at 0 min (P=0.000). There was statistically significant difference between TMP at 30 min[(84.39±25.80)mmHg] and TMP at 0 min[(80.78±27.69)mmHg] (P=0.036). There was no significant difference in vital signs between the two groups at different time points (0, 15, 30 min), and there was no significant difference between different time points and 0 min. There was no significant difference in adverse events between the two groups. Conclusion It is safe to carry out early mobilities in ICU patients with c CRRT.
赵宏宇, 唐晟, 马燕兰, 罗沙, 李丽娜, 曹玉蕤, 杨宁. ICU连续性肾脏替代治疗患者早期活动对安全性的影响[J]. 武警医学, 2022, 33(5): 399-403.
ZHAO Hongyu, TANG Sheng, MA Yanlan, LUO Sha, LI Lina, CAO Yurui, YANG Ning. Effect of early mobilities on safety in ICU patients with continuous renal replacement therapy. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(5): 399-403.
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