Abstract：Objective To explore the quantitative evaluation of right ventricular myocardial work in patients with chronic heart failure (CHF) by pressure-strain loop (PSL).Methods Sixty patients with clinically confirmed CHF in Jingzhou Central Hospital from December 2021 to June 2022 were selected as the case group. and they were divided into non-pulmonary hypertension group (NPH group) and pulmonary hypertension group (PH group) according to whether the pulmonary artery systolic pressure (PASP) was >40 mmHg, and thirty healthy volunteers were selected as the control group during the same period. All study subjects underwent routine echocardiography to obtain routine ultrasound parameters: right ventricular area change fraction (RVFAC), tricuspid annular peak systolic velocity (S'), and tricuspid annular plane systolic excursion (TAPSE), etc. Right ventricular global longitudinal strain (RVGLS) and right ventricular myocardial work parameters were obtained by EchoPAC work station, including right ventricle global work index (RVGWI), right ventricle global constructive work (RVGCW), right ventricle global wasted work (RVGWW) and right ventricle global work efficiency (RVGWE), and the differences of each parameter between the three groups were compared.Results Compared with the control group, RVFAC, S', and TAPSE decreased, RVGLS, RVGWI, RVGCW, and RVGWE also decreased, and RVGWW increased in the NPH and PH groups, with statistically significant differences (P<0.05).Compared with the NPH group, there were no statistical differences in RVFAC, S', and TAPSE, RVGLS decreased, RVGWI, RVGCW and RVGWW increased with statistically significant differences(P<0.05), and there were no statistical differences in RVGWE.Conclusions PSL is independent of afterload and available to detect abnormal right ventricular myocardial systolic function early in patients with CHF, providing a novel evaluation method for assessing the degree of myocardial involvement.
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2023, Vol. 34 
