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| Effect of transient intensive insulin treatment on insulin resistance in newly diagnosed type 2 diabetic patients |
| WU Jinxiao, XU Xiuping, JIAO Xiumin, ZHANG Xingguang, CHEN Bin, and LV Xiaofeng. |
| Department of Endocrinology, General Hospital of Beijing Military Command, Beijing 100700，China |
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Abstract Objective To evaluate the variance of insulin resistance after continuous subcutaneous insulin infusion (CSⅡ) or multiple subcutaneous injection (MSⅡ) therapy in newly diagnosed type 2 diabetic patients. Methods Sixty newly diagnosed type 2 diabetic patients were randomly divided into two groups: CSⅡ and MSⅡ group. SIM were calculated to evaluate the variance of insulin sensitivity. Results SIM（26.98±11.99）were significantly higher in CSⅡ group than （22.14±9.00）in MSⅡ group, P =0.042. Conclusions Short-term CSⅡ can effectively increase insulin sensitivity in newly diagnosed type 2 diabetic
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Received: 02 January 2012
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