|
|
Changes in p-selection and glycoprotein Ⅱb/Ⅲa on the surface of platelets between healthy individuals and elderly patients with coronary heart disease(CHD) |
XIONG Zhijian1,LI Dandan1,LI Hong2,ZOU Hui1,ZHANG Liping1,and DU Xunhui1. |
1.Department of Geriatrics,the General Hospital of PLA,Beijing 100853,China;2. Department of Cardiology,Second Hospital of Nanchang,330003 China |
|
|
Abstract Objective To investigate the changes in tyrosine phosphatase(CD148),P-selection (CD62P) and glyco1protein Ⅱb/Ⅲa(PAC-1) in platelets of elderly patients with coronary heart disease(CHD).Methods CD148,CD62P and PAC-1 in platelets were analyzed by flow cytometric 3-color immunofluorescence.Results The percentage and MFI of CD62 expression in the platelet membrane in elderly patients with coronary heart disease(CHD) were increased compared with healthy individuals(6.24 vs 0.89,P
|
Received: 14 March 2012
|
|
|
|
|
[1] |
. [J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(9): 737-740. |
|
|
|
|