尿毒症患者透析前后周围神经的电生理指标变化

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Abstract Objective To analyze electrophysiological changes in uremic patients before and after hemodialysis. Methods Twenty-three hemodialysis patients were enrolled and electrophysiological tests were performed before and after hemodialysis ,including tibial nerve, peroneal nerve,sural nerve, and the skin sympathetic response. The electrophysiological changes were observed and the relations between electrophysiological parameters and blood parameters in uremic dialysis patients before and after hemodialysis were analyzed. Results The main electrophysiological changes were prolongated F wave latency of tibial nerve,slowing of nerve conduction, prolongated distal latencies, decreased amplitude.Comparison before and after hemodialysis showed that the motor and sensory nerve,skin sympathetic response had a significant difference (P<0.01 or P<0.05). The F wave latency of posterior tibial nerve and Cr were positively correlated; the latency of distal posterior tibial nerve and K was positively correlated,with its amplitude and BUN,P negatively correlated.The motor conduction velocity of posterior tibial nerve and UA were negatively correlated, with its amplitude and Mg,K negatively correlated.The sensory conduction velocity of common peroneal nerve and Cr,Bun were negatively correlated;the motor conduction velocity of common peroneal nerve and Cr were negatively correlated.The sensory conduction velocity of sural nerve and Cr,BUN were negatively correlated. Conclusions After hemodialysis the abnormal peripheral neuropathy in uremic patients is improved significantly,its change is in conformity with the change in.Electrophysiological examination can be used as an important auxiliary examination to observe the progression of the disease and to evaluate the therapeutic effect.

Key words： electrophysiology uremic peripheral neuropathy hemodialysis

Received: 13 July 2012

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	LI Ping
	WU Ting-Ting
	QIAO Hui
	LIU Yang

Cite this article:

LI Ping,WU Ting-Ting,QIAO Hui等. Electrophysiological changes in uremic dialysis patients before and after hemodialysis[J]. , 2012, 23(12): 1020-1022.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2012/V23/I12/1020

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