血清Chemerin与2型糖尿病合并冠心病的相关性

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Abstract Objective Chemerin is a newly discovered adipokine. This aim of the study was to determine the association of serum chemerin levels with the development of type 2 diabetes mellitus accompanied by coronary artery disease. Methods This study consisted of 256 patients with type 2 diabetes mellitus: 156 without coronary artery disease and 100 with coronary artery disease. Serum chemerin levels were investigated in the two groups by enzyme-linked immunosorbent assay. Multivariable logistic regression analysis was used to analyze the correlation between type 2 diabetes mellitus and the coronary artery disease. Results Type 2 diabetes mellitus patients with combined coronary artery disease showed significantly elevated serum chemerin levels compared with those without coronary artery disease. Serum chemerin level was a determinant parameter of the presence of coronary artery disease in type 2 diabetes mellitus patients. Conclusions Serum chemerin level can serve as a predictive serum marker for the development of coronary artery disease in type 2 diabetes mellitus patients.

Key words： serum chemerin diabetes mellitus, type 2 coronary artery disease inflammation

Received: 25 March 2014

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	Articles by authors
	LAN Li-Juan
	LI Hong-Tao
	WANG Xiao-Dong
	YAO Min
	YANG Tao
	LI Cheng-Liang
	LIU Wei

Cite this article:

LAN Li-Juan,LI Hong-Tao,WANG Xiao-Dong等. Association of serum chemerin levels with type 2 diabetes mellitus accompanied by coronary artery disease[J]. , 2014, 25(8): 777-779.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2014/V25/I8/777

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