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| Application of general anesthesia without muscle relaxant in nasal endoscopic surgery |
| YANG Gexiong1, YUAN Jie2, GAO Shuang1, LI Tao1,TENG Yu1, and MA Junling1 |
1.Department of Anesthesia,
2. Department of Urinary, Xinjiang Uygur Autonomous Region Corps Hospital of Chinese People’s Armed Police Forces, Urumqi 830091,China |
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Abstract Objective To investigate the effect and feasibility of anesthesia without muscle relaxant in nasal endoscopic operation. Methods 120 patients with ASA Ⅰ-Ⅱundergoing nasal endoscopic operation were randomly divided into normal muscle relaxant use group (group Ⅰ) and intubation without muscle relaxant maintenance group (groupⅡ), 60 cases in each. Group Ⅰ was treated with vecuronium 0.08-0.1 mg/kg induced, in patients with body movement or per 40min intravenous infusion of 0.05 mg/kg maintaining muscle relaxation; group Ⅱtracheal intubation after complex full airway surface anesthesia but without muscle relaxants maintenance during operation. Blood pressure (MAP), heart rate (HR), pulse oxygen saturation (SpO2), end tidal carbon dioxide partial pressure (PetCO2) were recorded in each time point in the two groups before anesthesia (T0), 2 min after anesthesia induction (T1), 2 min after endotracheal intubation (T2), 2 min after the start of operation (T3), 20 min after the start of operation (T4), and 5 min after extubation (T5). The body movement frequency intraoperation , recovery time from anesthesia and extubation time, adverse reactions and complications and intraoperative additional infusion dosage of remifentanil and propofol were compared between the two groups. Results In both groups, T0～T4 each observation point,HR, MAP, SpO2 and PetCO2 changes were not significantly different (P>0.05). Breathing the air after 5 min(T5), SPO2 in group Ⅱ were higher than those in group Ⅰ, PetCO2 in groupⅡlower than that in group Ⅰ, there were significant differences between the two groups (P<0.05). In group Ⅱ,anesthesia recovery time and extubation time were significantly shorter than those in group Ⅰ(P<0.01). There were no adverse reaction and complication. Conclusions The effect of nasal endoscopic surgery under tracheal intubation general anesthesia without muscle relaxant is reliable, safe and feasible.
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Received: 01 June 2014
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2014, Vol. 25 
