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| Relationship between serum lipoprotein(a) levels and five disease in the elderly male patients |
| LI Taoyi1,ZHAO Haibin2,WANG Dan3, LI Kai3,and YANG Changchun3 |
1. The Outpatient Department of the Chinese People’s Armed Police Forces Fire Department, Beijing100000, China;
2. Department of Clinical Laboratory,
3. First Department of South Building,General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China |
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Abstract Objective To investigate the level changes of serum lipoprotein(a),further to provide the evidence for early diagnosis in the elderly male patients. Methods 442 hospitalized elderly male patients between June 2011 and December 2012 were enrolled in this study. Other 80 healthy elderly male subjects served as control group. The levels of serum Lp(a) were measured by latex agglutination turbidimetric method. Results Compared with the control group, the level of Lp(a) was significantly increased in disease group( P＜0.05 ),the levels of Lp (a) in control group was(154±110)mg/L,the level of Lp (a) in the high blood pressure,diabetes mellitus,coronary heart disease,cerebral infarction and renal insufficiency group respectively were(255±191),(266±174),(341±342),(335±277), and (296±235)mg/L respectively. The abnormal ratio in control serum was 6.0%, the abnormal ratios in the high blood pressure, diabetes mellitus, coronary heart disease,cerebral infarction, and renal insufficiency groups were 25.7%, 38.9%, 52.4%, 42.3%, and 37.2 %, respectively; the differences were statistically significant as compared with the control group (P＜0.05). The LP (a) levels of age group were no statistical difference. Conclusions The levels of serum LP (a) are significantly increased in elderly male patients with high blood pressure,diabetes,coronary heart disease,cerebral infarction, and renal insufficiency, regardless of age.
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Received: 05 July 2014
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2014, Vol. 25 
