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Ventriculopuncture combined with trans-posterior fossa craniotomy in treatment of intraventricular hemorrhage |
HU Huihua,CHANG Huimin, YAO Xuefeng |
Department of Neurosurgery,Guangdong Provinicial Corps Hospital, Chinese People’s Armed Police Forces, Guangzhou 510507,China |
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Abstract Objective To evaluate the clinical value of ventriculopuncture combined with the trans-posterior fossa craniotomy in treatment of intraventricular hemorrhage. Methods In retrospective analysis of clinical data of neurosurgery department from October 2010 to October 2014,there were 80 hypertensive intraventricular hemorrhage patients in the study group (40 cases) and control group (40 cases). The study group patients were treated with ventriculopuncture combined with trans-posterior fossa craniotomy and urokinase fibrinolytic therapy; the control group patients were treated with ventriculopuncture and urokinase fibrinolytic therapy. And analysis of their prognosis was made. Results The hematoma in the lateral ventricle,the third ventricle and the fourth ventricle were removed postoperatively,the removal time of hematoma in study group was (5±2) days, compared with (9±3) days in the control group, with statistically significant difference (P<0.01); and the mortality was 5% in the study group,compared with 22.5% in the control group, the difference was significant (P<0.01). The activities daily living score (ADL) in surviving patients improved in the following 6 months(P<0.05). Conclusions Ventriculopuncture combined with trans-posterior fossa craniotomy in treatment of intraventricular hemorrhage is effective, which significantly reduces the mortality rate and improves the prognosis of patients.
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Received: 04 November 2014
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Chi F L, Lang T C, Sun S J, et al. Relationship between different surgical methods, hemorrhage position, hemorrhage volume, surgical timing, and treatment outcome of hypertensive intracerebral hemorrhage[J]. World J Emerg Med,2014,5(3): 203-208.
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李 越, 欧海荣,杨 朔, 等. 脑室穿刺结合腰大池穿刺持续引流治疗40例脑室铸型出血的疗效分析[J]. 广东医学院学报,2011, 29(1): 67-68.
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[6] |
黄华东, 黄海能, 邓元央,等. 联合术式对高血压脑出血合并脑疝患者预后的影响[J]. 重庆医学,2013, 42(1): 65-67.
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王 刚, 田力学, 吕新兵,等. 神经内镜结合小骨窗治疗高血压脑出血[J].中华神经外科杂志,2010, 26(9): 826-828.
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Ziai W C, Tuhrim S, Lane K, et al. A multicenter, randomized, double-blinded, placebo-controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR Ⅲ)[J]. Int J Stroke, 2014, 9(4): 536-542.
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[7] |
阮玉山, 肖绍文,罗 昱, 等. 双腔引流管持续冲洗引流治疗超早期高血压脑室出血[J]. 中国微侵袭神经外科杂志,2010,15(3): 108.
|
[8] |
董建平, 罗志伟, 顾伟红,等. 神经内镜与传统钻孔手术治疗脑室铸型出血[J]. 中华神经外科疾病研究杂志,2011, 10(3): 265-266.
|
[9] |
游 涛, 谭兴萍, 文晓琴,等. 神经内镜辅助超早期手术治疗丘脑出血破入脑室[J]. 广东医学, 2013, 33(24): 3838.
|
[10] |
王 刚, 田力学, 吕新兵,等. 神经内镜结合小骨窗治疗高血压脑出血[J].中华神经外科杂志,2010, 26(9): 826-828.
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[11] |
Ziai W C, Tuhrim S, Lane K, et al. A multicenter, randomized, double-blinded, placebo-controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR Ⅲ)[J]. Int J Stroke, 2014, 9(4): 536-542.
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