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Received: 02 December 2014
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Bonafede M, Johnson B H, Fox K M.Treatment patterns with etanercept and adalimumab for psoriatic diseases in a real-world settings[J].J Dermatol Treat,2013,24(5): 369-373.
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Ivanov I I, Zhou L, Littman D R. Transcriptional regulation of Th17 cell differentiations[J]. Seminars in Immunology, 2007,19(6):409-417.
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Kimball A B, Gordon K B, Langely R G, et al. Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody in the treatment of moderate to severe chronic plaque psoriasis[J]. Arch Dermatol,2013,144:200-207.
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Papp K, Leonardi C, Menter A,et al.Safety and efficacy of brodalumab for psoriasis after 120 weeks of treatment[J].J Am Acad Dermatol,2014,71(6):1183-1190.
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Kavanaugh A, McInnes I, Mease P, et al. Golimumab, a new human tumor necrosis factor α, administered every four weeks as a subcutaneous injection in psoriatic arthritis: twenty-four-week efficacy and safety results of a randomized, placebo-controlled studys[J]. Arthritis Rheum, 2009,60:976-986.
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Langley R G, Elewski B E, Lebwohl M,et al.Secukinumab in plaque psoriasis--results of two phase 3 trials[J].N Engl J Med, 2014,371(4):326-338.
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Kavanaugh A, Vander H D, McInnes I B, et al.Golimumab in psoriatic arthritis: one-year clinical efficacy, radiographic, and safety results from a phase III, randomized, placebo-controlled trial[J]. Arthritis Rheum,2012,64(8):2504-2517.
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Ren V, Dao H.Potential role of ixekizumab in the treatment of moderate-to-severe plaque psoriasis[J].Clini Cosme Investigat Dermatol, 2013,6:75-80.
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Bonafede M, Johnson B H, Fox K M.Treatment patterns with etanercept and adalimumab for psoriatic diseases in a real-world settings[J].J Dermatol Treat,2013,24(5): 369-373.
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Schafer P H, Parton A, Gandhi A K, et al. Apremilast, a cAMP phosphodiesterase-4 inhibiter, demonstrates antiinflammatory activity in vitro and in a model of psoriasis[J]. British Jonrral of Pharmacology, 2010,159(4):842-855.
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| [13] |
Ivanov I I, Zhou L, Littman D R. Transcriptional regulation of Th17 cell differentiations[J]. Seminars in Immunology, 2007,19(6):409-417.
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Palfreeman A C, McNamee K E, McCann F E.New developments in the management of psoriasis and psoriatic arthritis: focus on apremilast[J].Drug Des Devel Ther,2013,7:201-210.
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Kimball A B, Gordon K B, Langely R G, et al. Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody in the treatment of moderate to severe chronic plaque psoriasis[J]. Arch Dermatol,2013,144:200-207.
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Matz M, Naik M, Mashreghi M F, et al. Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation[J]. Expert Opin Drug Meta Toxico,2011,7(1):103-113.
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Papp K, Leonardi C, Menter A,et al.Safety and efficacy of brodalumab for psoriasis after 120 weeks of treatment[J].J Am Acad Dermatol,2014,71(6):1183-1190.
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He X, Koenen H J, Smeets R L, et al.Targeting PKC in human T cells using sotrastaurin (AEB071) preserves regulatory T cells and prevents IL-17 production[J]. Invest Dermatol,2014,134(4):975-983.
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Westra J, Doornbosvan B, Deboer P,et al. Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor[J].Arthritis Research & Therapy, 2004,6(4):R384-R392.
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Ortiz I K, Alsina M M, Munoz-Santos C. Tofacitinib and other kinase inhibitors in the treatment of psoriasis[J].Actas Dermo-Sifiliograficas,2013,104(4):304-310.
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Raychaudhuri S P, Sanyal M, Weltman H, et al.K252a, a high-affinity nerve growth factor receptor blocker, improves psoriasis: an in vivo study using the severe combined immunodeficient mouse-human skin model[J]. J Invest Dermatol,2004,122(3):812-819.
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| [25] |
Wada Y, Cardinale I, Khatcherian A, et al. Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis[J].PLoS ONE,2012,7(4):e35069.
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| [16] |
Langley R G, Elewski B E, Lebwohl M,et al.Secukinumab in plaque psoriasis--results of two phase 3 trials[J].N Engl J Med, 2014,371(4):326-338.
|
| [17] |
Ren V, Dao H.Potential role of ixekizumab in the treatment of moderate-to-severe plaque psoriasis[J].Clini Cosme Investigat Dermatol, 2013,6:75-80.
|
| [18] |
Schafer P H, Parton A, Gandhi A K, et al. Apremilast, a cAMP phosphodiesterase-4 inhibiter, demonstrates antiinflammatory activity in vitro and in a model of psoriasis[J]. British Jonrral of Pharmacology, 2010,159(4):842-855.
|
| [19] |
Palfreeman A C, McNamee K E, McCann F E.New developments in the management of psoriasis and psoriatic arthritis: focus on apremilast[J].Drug Des Devel Ther,2013,7:201-210.
|
| [20] |
Matz M, Naik M, Mashreghi M F, et al. Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation[J]. Expert Opin Drug Meta Toxico,2011,7(1):103-113.
|
| [21] |
He X, Koenen H J, Smeets R L, et al.Targeting PKC in human T cells using sotrastaurin (AEB071) preserves regulatory T cells and prevents IL-17 production[J]. Invest Dermatol,2014,134(4):975-983.
|
| [22] |
Westra J, Doornbosvan B, Deboer P,et al. Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor[J].Arthritis Research & Therapy, 2004,6(4):R384-R392.
|
| [23] |
Ortiz I K, Alsina M M, Munoz-Santos C. Tofacitinib and other kinase inhibitors in the treatment of psoriasis[J].Actas Dermo-Sifiliograficas,2013,104(4):304-310.
|
| [24] |
Raychaudhuri S P, Sanyal M, Weltman H, et al.K252a, a high-affinity nerve growth factor receptor blocker, improves psoriasis: an in vivo study using the severe combined immunodeficient mouse-human skin model[J]. J Invest Dermatol,2004,122(3):812-819.
|
| [25] |
Wada Y, Cardinale I, Khatcherian A, et al. Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis[J].PLoS ONE,2012,7(4):e35069.
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2015, Vol. 26 
