阻塞性睡眠呼吸暂停低通气综合征对骨组织的影响

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Abstract Objective To study the impact of obstructive sleep apnea hypopnea syndrome(OSAHS) on bone issue. We compared the bone mineral density (BMD) between the patients with OSAHS and those who are simply snoring patients. Methods 126 male snoring patients are underwent the polysomnography(PSG). According to the apnea hypopnea index (AHI),they were divided into snoring group (32 cases),mild OSAHS group (29 cases), moderate OSAHS group(35 cases),and severe OSAHS group (30 cases); part BMD and total body BMD were determed. We compared mild, moderate and severe OSAHS groups with the simply snoring group, respectively. Results 1. Part BMD and total body BMD in the severe OSAHS group were lower than those in the snoring group, and the difference was statistically significant(P＜0.05). 2. Part BMD in the moderate OSAHS group was lower than in the snoring group,and the difference was statistically significant (P＜0.05). 3.Comparing mild OSAHS group with the snoring group, there was no significant difference(P＞0.05). Conclusion OSAHS is a risk factor of osteoporosis. The BMD in OSAHS patients decreases gradually with the aggravating of the illness.

Key words： obstructive sleep apnea-hypopnea syndrome bone mineral density osteoporosis

Received: 05 January 2015

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	DUAN Zhijuan
	LI Yuanyuan
	ZHU Xu
	YANG Yun

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DUAN Zhijuan,LI Yuanyuan,ZHU Xu等. A clinical study of bone mineral density in patients with obstructive sleep apnea hypopnea syndrome[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(9): 869-872.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I9/869

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