脉冲电磁场结合自体红骨髓移植治疗创伤性骨缺损的疗效

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Abstract Objective To study clinical effects of the pulsed electromagnetic fields(PEMFs) combined with autologous red marrow implantation in the treatment of traumatic bone defect.Methods Patients with fresh fractures of the limbs were divided into three groups randomly. The allograft cancellous bone was implanted into the bone defect region before routine fixation in the control group. For 2 Hz and 15 Hz study groups, internal fixation was carried out after the blended autologous red marrow and allograft cancellous bone were implanted, then treated with PEMFs of 2 Hz, 15 Hz. X-ray examination was performed at 4,12,24,40 weeks after fixation in all patients and the effects were evaluated.Results All the 30 patients were followed up after treatment, the cure rates in control group, 2 Hz, 15 Hz study groups were 80%, 100%, 90%, respectively. The formation of bony callus in the study groups were significantly higher than that in the control group at the same time point (P<0. 05), and the formation of bony callus in PEMFs group of 2 Hz was higher than those in the group of 15 Hz (P<0. 05). The functional recovery of upper and lower limbs had no significant difference between the three groups (P<0.05).Conclusions PEMFs combined with the composite of allograft cancellous bone and autologous red marrow can promote the growth of bony callus significantly, and is effective to repair bone defects.

Key words： pulsed electromagnetic fields autologous red marrow allograft cancellous bone bone defect composite graft

Received: 28 December 2015

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	Articles by authors
	LI Bin
	CHENG Huayong
	GAO Hao
	LIU Li
	ZHU Xu
	LI Yongguang
	and LU Xiaogang

Cite this article:

LI Bin,CHENG Huayong,GAO Hao等. Pulsed electromagnetic fields combined with autologous red marrow transplantation for treatment of traumatic bone deffect[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(6): 550-552.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2016/V27/I6/550

[1]	Peter V G,Haralambos D,Eleftherios T. Bone substitutes:an update[J].Injury,2005,36(3):20-27.
[2]	Ryang We S,Koog Y H,Jeong K I,et al.Effects of pulsed electromagnetic field on knee osteoarthritis:a systematic review [J].Rheumatology,2013,52(5):815-824.
[3]	虞冀哲,杨勇,刘朝旭,等.共培养条件下电磁场干预对大鼠成骨细胞及骨髓间充质干细胞成骨分化的影响[J].中华物理医学与康复杂志,2013,35(4):250-255.
[4]	刘纪涛,陶军.2Hz极低频脉冲电磁场可促进金属植入物内固定四肢新鲜骨折的愈合[J].中国组织工程研究与临床康复,2011,15(52):9709-9712.
[5]	Kong Zhigang,Chen Yongbao,Sun Lei.Allograft cancellous bone combined with autologous red marrow for treatment of periarticular fractures[J]. Chinese Journal of Tissue Engineering Research,2013,17(48):8419-8427.
[6]	Barnba S,Papalia R,Ruzzini L,et al.Effect of pulsed electromagnetic fields on human osteoblast cultures[J].Physiother Res Int,2013,18(2):109-114.
[7]	Assiotis A,Sachinis N P,Chalidis B E. Pulsed electromagnetic fields for the treatment of tibial delayed unions and nonunions.A prospective clinical study and review of the literature[J].Orthop Surg Res,2012,8(7):24.
[8]	Nozomu L,Isao O.Effect of pulsed electromagnetic fields (PEMF) on late-phase osteotomy gap healing in a canine tibial model[J].Orthop Res,2002,20(5):1106-1114.
[9]	蔡敏,李宏宇.四肢骨不连治疗方法的研究进展[J].中国矫形外科杂志,2012,20(6):534-536.