腹腔镜直肠癌根治术后吻合口瘘的危险因素

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (586 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the risk factors for anastomotic leakage in patients who have undergone laparoscopic radical resection for rectal cancer. Methods The clinical data of 146 patients treated at the First Hospital of Shanxi Medical University between June 2014 and June 2018 was retrospectively analyzed. Results Surgery was successful in all cases without conversions to open operation. The overall anastomotic leakage rate was 8.90%(13 of 146) and 10 cases were observed in males and 3 cases in females only. The occurrence of anastomotic leakage was related to the preoperative albumin level, the distance between the lower edge of the tumor and the anus, and the number of linear staplers used during the operation. The incidence of anastomotic leakage was higher in patients with preoperative albumin levels lower than 35 g/L, the distance between the lower edge of the tumor and the anus shorter than 7 cm, and the number of linear staplers used intraoperatively (P=0.013,P=0.037,P=0.011). Multivariate analysis showed that preoperative albumin levels (OR=4.092, 95% CI: 1.231-13.602) and intraoperative use of occluders (OR=4.272, 95% CI: 1.285-14.202) were independent risk factors for anastomotic leakage. Conclusions Low preoperative albumin levels(＜35 g/L), the number of linear staplers used during operation, and the distance between the lower edge of the tumor and the anus less than 7 cm are risk factors for anastomotic leakage after laparoscopic radical resection for rectal cancer. Surgeons should pay more attention to patients with one or more of these indications, and necessary preventive measures should be taken.

Key words： rectal cancer anastomotic leakage risk factors

Received: 10 October 2018

ZTFLH:

R735.34

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CHEN Hao
	XIONG Yongqiang
	HUANG He

Cite this article:

CHEN Hao,XIONG Yongqiang,HUANG He. Risk factors for anastomotic leakage after laparoscopic radical resection for rectal cancer[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(4): 322-324.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2019/V30/I4/322

[1]	Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2018,10:1-31.
[2]	Kanellos D, Pramateftakis M G, Vrakas G, et al. Anastomotic leakage following low anterior resection for rectal cancer[J]. Tech Coloproctol, 2010, 14(1):35-37.
[3]	何元. 瘤体下缘距肛门不同距离对直肠癌双吻合术后吻合口瘘预防效果的影响[J]. 结直肠肛门外科, 2016(2):160-163.
[4]	王新, 周建平, 张丹华,等. 直肠癌术后发生吻合口瘘危险因素分析(附506例报告)[J]. 中国实用外科杂志, 2014, 34(9): 876-879.
[5]	王道荣, 赵建国, 鱼海峰,等. 腹腔镜下超低位直肠癌根治术后吻合口瘘的预防和处理[J]. 外科理论与实践, 2011, 16(6): 589-591.
[6]	崔潇龙, 黄河, 郭云童,等. C反应蛋白在结直肠癌术后吻合口瘘早期预测的临床价值[J]. 中国药物与临床, 2016, 16(9):1356-1358.
[7]	吴国刚, 刘兆润, 冷梅,等. 降钙素原与C反应蛋白在预测结直肠癌手术后吻合口瘘的临床价值[J]. 中华普通外科学文献(电子版), 2018, 12(4):228-232.

[1]	. [J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(6): 549-549.