某部队医院2013-2018年真菌血流感染菌种分布和耐药性分析

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Abstract Objective To investigate the current fungal blood stream infections and to provide reference for the prevention and treatment of fungemia.Methods Retrospective analysis was used to test the results of fungal blood stream infections in a military hospital between 2013 and 2018. The species, distribution and drug resistance were analyzed.Results 97 strains of fungal blood stream infections were isolated, mainly Candida albicans(30.93%), but the proportion decreased(from 41.76% in 2013 to 27.78% in 2018). Fungal blood stream infections occurred most often in departments of hematology(24.74%) and intensive care medicine (22.68%). The sensitivities to four antimicrobial agents were as follows: 5-fluorocytosine (97.80%), voriconazole (97.80%), fluconazole (93.30%), and itraconazole (71.10%).Conclusions Candida albicans is the main fungus associated with blood stream infections, but infections with non-Candida albicans are on the rise. Improving immunity and reducing invasive examination and treatment are important to reduce fungal blood flow in fection.Triazoles are still the mainstream antifungal drugs, and resistance needs to be tested in the course of treatment.

Key words： blood stream infection fungus fungemia analysis

Received: 20 January 2019

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	Articles by authors
	LI Jixia
	XUE Lian
	WU Jing
	CUI Hairong
	MIN Yan
	SUN Xiao

Cite this article:

LI Jixia,XUE Lian,WU Jing等. Distribution and drug resistance of fungal blood stream infections in a military hospital from 2013 to 2018[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(9): 772-775.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2019/V30/I9/772

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