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Safety of ongoing pregnancy after multidisciplinary surgical management of hemorrhagic cerebrovascular disease |
HAN Dan1, GAO Wanli1, LIANG Zhuwei1, WANG Shuo2, ZHAO Jizhong2, MENG Shihui1, LI Yanrong1 |
1.Deperment of Obstetrics and Gynecology, 2.Deperment of neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China |
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Abstract Objective To explore the safety of ongoing pregnancy after multidisciplinary management of hemorrhagic encephalopathy. Methods Six pregnant patients with hemorrhagic encephalopathy admitted to Beijing Tiantan Hospital between January 2013 and August 2016 were enrolled into this study, all of whom were diagnosed by multiple departments and treated by the Department of Neurosurgery. The postoperative obstetrics materials for ongoing pregnancy were analyzed. Consistent fetus monitoring was performed during operation. Results After 24-48 h at the ICU, the patients were transferred back to the obstetric wards and supervised in terms of their ongoing pregnancy. One case of midbrain aneurysm, one case of aneurysm with arteriovenous malformation, two cases of arteriovenous malformation, and two cases of spontaneous hemorrhagic cerebrovascular disease were treated with such approaches as aneurysmectomy, arteriovenous malformationectomy, crainiotomy, and intracranial hematoma drainage. The surgical sites included one left cerebellum, one right cerebellum, one occipital part of cerebrum, one right frontal lobe, one right posterior occipital lobe, one anterior artery and left middle cerebral artery. The size of the hematomas ranged from 3 to 5 cm, while onset gestational weeks ranged from 18 to 27 weeks. Five of the six pregnancies were singletons, and one was a twin, all of whom were full-term with birth weights ranging from 2320 to 3400 g. One fetus underwent preoperative and postoperative cerebrovascular radiation, and the total radiation dosage was 1.18 Rad. Conclusions Intraoperative anesthesia should be based on the patient’s condition. Radiation exposure should be limited. Hemodynamic stabilization and blood oxygen saturation should be maintained during operation. Postoperative multidisciplinary evaluation and treatment are needed so that the patient can continue pregnancy to full term.
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Received: 10 October 2019
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