食管癌微创手术后患者早期经口进食对胃肠功能恢复及其营养状态的影响

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Abstract Objective To investigate the effect of early oral feeding on the recovery of gastrointestinal function in patients with primary esophageal cancer after minimally invasive surgery, and to evaluate the nutritional status after surgery so as to provide data for the formulation of plans for accelerated rehabilitation surgery. Methods A total of 84 patients with primary esophageal cancer who had received minimally invasive surgery in our hospital between April 2015 and April 2020 were included in the study. These patients were randomly divided into the early oral feeding group and late oral feeding group,with 42 cases in each. The clinical data on the two groups of patients was collected while the time of the first postoperative exhaust and defecation was recorded. Serum levels of gastrin and motilin on the day of surgery and 1 d, 3 d, 5 d postoperatively were detected.The nutritional indexes of the body, including albumin (propagated), prealbumin (PAB)and transferrin (agency)before surgery and five days after surgery were recorded to find out about the incidence of malnutrition. Results There was no significant difference in basic clinical data between the two groups (P>0.05). The first postoperative exhaust time and defecation time were (2.04±0.72) d and (3.38±1.15) d respectively in the early oral feeding group, compared with (3.10±0.84) d and (4.82±1.09) d in the other group, so there was statistically significant difference between the two groups (P<0.05). There was no statistically significant difference in serum levels of gastrin and motilin between the two groups before surgery and 1 d after surgery,but these levels in the early oral feeding group were significantly higher than those of the late oral feeding group 3 d and 5d after surgery. The levels of ALB, PAB and TRF were not significantly different between the two groups before surgery, but they were significantly higher in the early oral feeding group than in the late oral feeding group 5 days after surgery (P<0.05). There was no significant difference in the incidence of postoperative anastomotic fistulas between the two groups. The incidence of malnutrition in the early oral feeding group was 16.67%, lower than (30.95%) in the late oral feeding group, and the difference was statistically significant (P<0.05). Conclusions Early oral feeding is of great clinical significance for accelerating gastrointestinal function recovery of patients with primary esophageal cancer after minimally invasive surgery,improving nutritional status,reducing the occurrence of malnutrition and accelerating postoperative recovery.

Key words： esophageal cancer early oral feeding gastrointestinal function recovery nutritional status

Received: 20 July 2021

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	SHI Xiaoyu
	WANG Huiqing

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SHI Xiaoyu,WANG Huiqing. Effects of early oral feeding on gastrointestinal function recovery and nutritional status in patients with esophageal cancer after minimally invasive surgery[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(3): 207-210.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2022/V33/I3/207

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