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Prospective cohort study on the relationship between tooth loss and all-cause death in the elderly of China |
LI Xiaofei, WANG Peihuan, FU Chongjian |
Department of Stomatology, the 960th Hospital of the Chinese PLA Joint Logistics Support Force,Jinan 250031, China |
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Abstract Objective To investigate the relationship between remaining tooth number and all-cause death in the elderly of China.Methods Based on Chinese Longitudinal Healthy Longevity Survey (CLHLS) from 2011 to 2018, the base line characteristics, the past medical history, and the number of remaining teeth of the respondents were obtained by the questionnaire. The activities of daily living and cognitive function were evaluated by Katz and MMSE scale, respectively. Multivariate Cox proportional hazards model was used to evaluate the association between the number of residual teeth and all-cause death.Results A total of 8658 participants were recruited in this study, with 3895 men (45.0%) and 4763 women (55.0%), and the average age was (85.7±11.2)years. After 7 years follow-up, 4488 participants died (51.8%) and the number of remaining teeth was negatively related with age (P<0.05). After adjusting for age, gender, BMI, smoking, drinking, exercise, hypertension, respiratory disease, cardiovascular disease, activities of daily living and cognitive function, multivariate Cox regression results showed that the risk of all-cause death decreased by 1% for each increase in the number of remaining teeth; compared with those with all teeth lost, the risk of all-cause death decreased by 22% in the elderly with ≥20 remaining teeth.Conclusions The decrease in the number of remaining teeth in the elderly population may increase the risk of all-cause death, and tooth loss in the elderly population should be prevented.
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Received: 18 January 2022
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