Abstract: Objective To investigate the major Influential factors of declined balance function in the elderly patients with knee osteoarthritis (KOA). Methods Eighty-nine elderly patients with KOA were tested with visual analogue pain scale (VAS), limits of stability (LOS), reaction time (RT), knee joint position sense, and isokinetic muscle strength.At the same time, their basic demographic information and the unaffected knees' radiological grades were collected. Results Under the premise of the age as a controlling factors, after the Pearson partial correlation analysis, we found that the total LOS score was closely correlated with the unaffected knees' factors such as VAS scores, RT, total response time (TRT), the reposition accuracy error mean and 60o of peak torque (P<0.05). And then after the multiple regression analysis, we found that the unaffected knees' reposition accuracy error mean, 60o of peak torque and RT among the above factors were major factors of the total LOS score(P<0.001). Conclusions Overweight, knee pain, course of knee osteoarthritis,and knees' radiological grades are not major influential factors that result in the declined balance function in the elderly patients with KOA. Compared with the balance function of the elderly people without KOA,that of the elderly patients' with KOA is worse. Whereas decreased lower extremity muscle strength resulting from knee pain, proprioception loss and slower sense reaction to new stimuli resulting from affected knee are the main characteristic influential factors of the declined balance function in the KOA patients.
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