1．TCM Branch of No.252 Hospital of PLA, Baoding 071000, Hebei, China; 2．Medical Team of No.66105 Troop, Baoding 071000, Hebei, China; 3．TCM Department of Hebei University,Baoding 071000,Hebei,China; 4．Institute of Traditional Chinese Medicine, Chinese PLA General Hospital, Beijing 100853, China
Abstract：Objective To observe the clinical effect of Zhihanchushi Powder on the localized hyperhidrosis and skin lesions in heat and humidity condition. Methods 550 military officers and soldiers in an unit were divided into 3 groups according to the foot sweating, genital organ sweating and tinea pedis. And these 3 groups were further divided into trial group and control group randomly. The trial group was provided with daily necessities plus Zhihanchushi Powder, while the control group used ordinary daily necessities. After 2 weeks, the hyperhidrosis areas were measured by the original seal record method, and the tinea pedis was microscopically examined and then subjected to germiculture. Results The trial group significantly improved after 2 weeks of continuous medication, compared with the control group. And the differences were statistically significant (P＜0.05). Conclusions The Zhihanchushi Powder can effectively prevent localized hyperhidrosis and tinea pedis.
郑莜萸．中药新药临床研究指导原则(试行) ［M］. 北京：中国医药科技出版社，2002: 295-298.［2］ Montain S T, Sawke M N, Cadarette B S, et al. Physiological tolerance to uncompensable heat stress; effects of exercise intensity, protective clothing and climate ［J］. J Appl Physiol, 1994, 77(7): 216.［3］ Wil B, Bar O. Effect of drink flavor and NaCl on voluntary drinking and hydration in boys exercising in heat［J］. J Appl Physol, 1996, 8(4):112.［4］ 陶胜来，陈晓琴，张源才. 缬沙坦联合苦参素治疗慢性乙型病毒性肝炎肝纤维化效果观察［J］. 临床误诊误治，2009，22(10)：76-77.［5］ 宋霞林，郭爱枝. 反相高效液相色谱法测定妇炎洗剂中苦参碱和氧化苦参碱的含量研究［J］. 中医药导报，2007，13(11)：71-72.［6］ 黎为能，谢金鲜. 蛇床子素药理作用的研究进展［J］. 时珍国医国药，2005，16(6)：530-531.［7］ 杨 娟，黄敬群. 除湿止汗散的制备及质量控制［J］. 中国医院药学杂志，2011, 31 (2): 154-156.(2012-08-25
［1］
郑莜萸．中药新药临床研究指导原则(试行) ［M］. 北京：中国医药科技出版社，2002: 295-298.［2］ Montain S T, Sawke M N, Cadarette B S, et al. Physiological tolerance to uncompensable heat stress; effects of exercise intensity, protective clothing and climate ［J］. J Appl Physiol, 1994, 77(7): 216.［3］ Wil B, Bar O. Effect of drink flavor and NaCl on voluntary drinking and hydration in boys exercising in heat［J］. J Appl Physol, 1996, 8(4):112.［4］ 陶胜来，陈晓琴，张源才. 缬沙坦联合苦参素治疗慢性乙型病毒性肝炎肝纤维化效果观察［J］. 临床误诊误治，2009，22(10)：76-77.［5］ 宋霞林，郭爱枝. 反相高效液相色谱法测定妇炎洗剂中苦参碱和氧化苦参碱的含量研究［J］. 中医药导报，2007，13(11)：71-72.［6］ 黎为能，谢金鲜. 蛇床子素药理作用的研究进展［J］. 时珍国医国药，2005，16(6)：530-531.［7］ 杨 娟，黄敬群. 除湿止汗散的制备及质量控制［J］. 中国医院药学杂志，2011, 31 (2): 154-156.(2012-08-25
2013, Vol. 24 
