Effect of combined direct and indirect bypass surgery on moyamoya disease in adults
HUANG Qihua1,LI Dongmei2,GAO Tian2,DU Shiwei2,WANG Jing2,BAI Zhifeng2,and MAO Gengsheng2.
1.Graduate School of Xuzhou Medical College, Xuzhou 221004, China;
2. Department of Nerve Vscaular Surgery, General Hospital of Chinese People’s Armed Police Forces,Beijing 100039,China
Abstract:Objective To study the effect of combined direct and indirect bypass surgery on moyamoya disease in adults. Methods 42 adult patients with non-hemorrhagic moyamoya disease were recruited as study subjects. And they were divided into control group and observation group.The patients in control group were treated by encephalo-duro-arterio-synangiosis (EDAS). And the observation group were treated with superficial temporal artery-middle cerebral artery anastomosis combined with encephaloduromyosynangiosis (STA-MCA+EDMS) . Then the focal cerebral perfusion and modified Rankin scale (mRS) before and after the treatment of two groups and the presentations of digital subtraction angiography(DSA) and complications after the treatment of two groups were analyzed and compared. Results The focal cerebral perfusion, mRS and presentations of DSA in observation group were better than those in control group, with significant differences (P<0.05). There were no complications after the treatment in the observation group. Conclusions The effect of the superficial temporal artery-middle cerebral artery anastomosis combining with encephaloduromyosynangiosis on non-hemorrhagic moyamoya disease in adults is better and it can significantly improve focal cerebral perfusion.
黄启化,李冬梅,高天,杜世伟,汪晶,白志峰,毛更生. 颅内外血管搭桥结合间接血运重建治疗成人烟雾病的疗效观察[J]. 武警医学, 2013, 24(6): 494-497.
HUANG Qihua,LI Dongmei,GAO Tian,DU Shiwei,WANG Jing,BAI Zhifeng,and MAO Gengsheng.. Effect of combined direct and indirect bypass surgery on moyamoya disease in adults. Med. J. Chin. Peop. Armed Poli. Forc., 2013, 24(6): 494-497.
Mesiwala A H, Sviri G, Fatemi N, et al. Long-term outcome of superficial temporal artery-middle cerebral artery bypass for patients with moyamoya disease in the US[J]. Neurosurg Focus, 2008, 24(2): 15.
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