Value of three-dimensional power Doppler imaging for early diagnosis of endometrial precancerous lesions
XI Mei1,QIAN Min2,LIU Weixing1,ZENG Li1,WEN Yuejun1,ZHANG Xuemei1,GUO Huiyue1,and BI Yingying1.
1. Department of Ultrasound, The General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China;
2. Department of Ultrasound,Affiliated Fuxing Hospital,Capital Medical University,Beijing 100038, China
Abstract：Objective To evaluate the value of three-dimensional power Doppler angiography (3D-PDA) in the discrimination between benign and endometrial precancerous lesions in women with bleeding. Methods Sixty-five women with bleeding who examined by 3D-PDA were enrolled. Endometrial volume(V), vascularity index(VI),flow index(FI) and vaseularity flow index(VFI)were measured with the comparison of the final pathology results. The diagnostic value of parameters derived from 3D- PDA was evaluated by using the receiver operating characteristic (ROC) curve.Results The majority of endometrial precancerous lesions in three-dimensional power Doppler angiography ultrasonography were abundant and rich, while endometrial benign lesions in three-dimensional power Doppler angiography ultrasonography were not rich. In benign group, VI, FI and VFI:3.98%?3.42%,21.13?3.15 and 0.643?0.328;in endometrial precancerous lesions group, VI, FI and VFI:5.903%?2.761%,28.964?2.446 and 1.705?0.928 when impulse repeat frequency (PRF) 0.9 MHz;differences of these parameters (VI,FI and VFI)were considered statistically significant between the two groups(P<0.05); differences of these parameters (VI,FI and VFI) were considered statistically significant in differences of PRF, 0.9 MHz/0.6 MHz(P<0.05); the parameters of endometrial volume had no significant differences between two groups;3D-PDA examination sensitivity was 88.9%, and specificity was 100%. the area under ROC curve (AUC) of the meaningful data were 0.851,0.772,0.950 respectively.Among these parameters,VFI had the highest diagnostic value for discriminating benign and endometrial precancerous lesions,the cut-off value of which was 0.81 with a sensitivity of 94.4%and a specificity of 12.8%.Conclusions 3D-PDA is a good diagnostic tool in the discriminations between benign and endometrial precancerous in women with bleeding.
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XI Mei,QIAN Min,LIU Weixing,ZENG Li,WEN Yuejun,ZHANG Xuemei,GUO Huiyue,and BI Yingying.. Value of three-dimensional power Doppler imaging for early diagnosis of endometrial precancerous lesions. Med. J. Chin. Peop. Armed Poli. Forc., 2013, 24(6): 511-514.
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2013, Vol. 24 
