摘要目的 观察地佐辛联合罗哌卡因用于臂丛神经阻滞的麻醉效果。方法 选择40例需行上肢手术的患者,随机分为A,B两组(每组20例)。各组均在超声引导下行臂丛神经阻滞,局麻药为0.5%罗哌卡因30 ml。A组不加地佐辛;B组局麻药中加入地佐辛10 mg。记录各组患者的麻醉起效时间、痛觉消失时间及镇痛持续时间。同时采用VAS评分评价患者麻醉后4、6、8 h的镇痛效果,并观察各组患者的不良反应。结果 B组的镇痛持续时间明显长于A组[(12.03±3.07) h vs (9.28±2.16) h,P<0.05)]。麻醉后8 h B组的VAS评分显著低于A组[(3.97±1.42) vs (6.38±2.32),P<0.05)],且无明显不良反应。结论 地佐辛联合罗哌卡因应用于臂丛神经阻滞能显著延长麻醉镇痛时间,且无明显不良反应。
Abstract：Objective To observe the effects of dezocine combined with ropivacaine in brachial plexus block. Methods Forty patients who were subjected to upper limb surgery were randomly divided into groups A and B (n=20 for each group ). The brachial plexus block was performed under ultrasound guiding with 0.5% ropivacaine 30 ml. In group A, no dezocine was added. Local anesthetic in group B consisted of dezocine 10 mg. Onset time of anesthesia,pain free time, duration of analgesia, postanethesia visual analogue scale(VAS) at 4, 6, 8 h and side effects were recorded. Results The duration of analgesia in group B was significantly longer than that in group A [(12.03?3.07) h vs (9.28?2.16) h, P<0.05)]. Postanesthesia VAS score at 8 h in group B was significantly lower than that in group A [(3.97?1.42) vs (6.38?2.32), P<0.05)]. There was no significant difference between group A and B about the incidence of side effects. Conclusion Dezocine combined with ropivacaine in brachial plexus block prolongs the analgesia with fewer side effects.
Nishikawa K. Fentanyl improves analgesic but prolongs the onset of axillary brachial plexus block by peripheral mechanism[J]. Anesth Analg, 2000, 91(2):384-387.
Nishikawa K. Fentanyl improves analgesic but prolongs the onset of axillary brachial plexus block by peripheral mechanism[J]. Anesth Analg, 2000, 91(2):384-387.
2014, Vol. 25 
