Changes and clinical significance of thyroid hormones function in elderly patients with chronic heart failure
ZHOU Qina1 DU Wenjuan2
1. Outpatient Department of Guizhou Provincial Corps Hospital, Chinese People’s Armed Police Forces, Guiyang 550005, China; 2. Department of Medical Affairs, General Hospital of PLA, Beijing 100853, China
Abstract:Objective To investigate the changes and clinical significance of thyroid hormones function in elderly patients with chronic heart failure. Methods A total of 76 elderly patients with chronic heart failure were divided into different groups according to NYHA categorization: NYHA Ⅱ group (25 patients), NYHA Ⅲ group (28 patients) and NYHA IV group (23 patients). Thirty non-heart failure elderly subjects served as control group. T3, T4, FT4, FT3, TSH were tested by radioimmunoassay. Results Compared with T3 and FT3 levels [(2.34±0.52)nmol/L and (4.27±0.64) pmol/L respectively] in control group, T3 and FT3 levels[(1.28±0.51) nmol/L and (3.01±0.78) pmol/L respectively] in NYHAⅡ group were decreased (P<0.05); and with the deterioration of cardiac function functional class Ⅲ-Ⅳ (P<0.01), patients showed T3 and FT3 levels [ (0.87±0.43) nmol/L and (2.42±0.61) pmol/L respectively] in NYHA Ⅲ group, and [ (0.60±0.36) nmol/L and (2.09±0.71) pmol/L respectively ] in NYHA IV group. Conclusions T3 and FT3 play an important role in chronic heart failure, can serve as the early predictors in elderly patients with chronic heart failure.
周齐娜,杜文娟. 老年慢性心力衰竭患者甲状腺激素的变化及其临床意义[J]. 武警医学, 2014, 25(10): 997-998.
ZHOU Qina DU Wenjuan. Changes and clinical significance of thyroid hormones function in elderly patients with chronic heart failure. Med. J. Chin. Peop. Armed Poli. Forc., 2014, 25(10): 997-998.