Abstract：Objective To investigate the dynamic changes of myocardial injury markers in blunt trauma patients’ serum and its significance in diagnosis of trauma complicated by myocardial injury. Methods According to the presence or absence of myocardial injury, 82 cases of blunt trauma patients (ISS≥16) from December 2011 to December 2013 in this hospital were assigned to group A (presence of myocardial injury) and B (absence of myocardial injury). Troponin Ⅰ (cTnI), heart fatty acid-binding protein (H-FABP) , and myoglobin (Mb) were detected 3 h, 6 h, 12 h, 48 h after injury in serum of group A, B and 60 healthy persons (control group). Results Concentrations of cTnI, H-FABP and Mb were significantly higher than those in the control group at different times. Concentrations of cTnI and H-FABP in group A were significantly higher than those in group B (P<0.01). The concentration of Mb in group A, B was higher than that in control group, but the difference between the groups A and B was not significant (P＞0.05). Conclusions There is a good correlation between the dynamic changes of cTnI, H-FABP and Mb in serum and severity of illness, variation tendency and prognosis of blunt chest trauma patients, which is important for early diagnosis and treatment of myocardial injury. Combined with other examination Methods (X-ray, ECG, blood gas analysis, color Doppler echocardiography), detection of myocardial injury markers has a high clinical value in treatment of blunt chest trauma complicated by myocardial injury.
Moammar M Q, Ali M I, Mahmood M A, et al.Cardiac troponin Ilevels and alveolar-arterial oxygen gradient in patients with community-acquired Pneumonia[J].Heaet Lung Circ, 2010, l9(2):90-92.
2015, Vol. 26 
