Abstract:Objective To investigate of acute myocardial infarction (referred to as AMI) the problems of accuracyinICD-10 classification and coding, and analyzeits causes of error, and countermeasures. Methods 348 copies of medical records ofinpatientsfrom November 2013 to October 2014 in this hospital with discharge diagnosis code of I21.-,were consulted. Results In the 348 copies of medical record with discharge main diagnosis coded as I21.-, the total code error rate was 33.91%. Conclusions The hospital leadership should invite experts to hold ICD-10 related lectures,so as clinicians have the opportunity to learn about the content of ICD-10, writestandard disease diagnosis, as complete and specific as possible.The coding staffshould find problems in the work hard,learnbasic knowledge of ICD-10,be familiar with ICD-10 structure, learn the relevant medical knowledge, carefully communicate with clinicians, when necessary, to correct code, and constantly improve their coding skills.