Significance of monitoring pulse oxygen saturation during primary percutaneous coronary intervention with ST-segment elevation myocardial infarction
WANG Honglei1, DONG Pingshuan1, SHANG Xiyan1, XING Shiying1, LI Zhiguo1, ZHANG Huifeng1, HAN Yanhui1, and ZHANG Weiwei2
1.Department of Cardiology, The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471003, China; 2.education department of bio-tech and park education, pharmaceutical and bio-engineering school, Zibo Vocational Institute, Zibo 255314,China
Abstract:Objective To study the relationship between pulse oxygen saturation (SpO2) during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) and its clinical efficacy and prognostic value. Methods We studied 132 STEMI patients for whom pulse oxygen saturation was monitored continuously during primary PCI. According to the pS02, the patients were divided into the observation group(n=64, SpO2<90%) and the control group (n=68, SpO2≥90%). We observed the number of the stenotic vessls, left ventricular end-systolic volume(LVESV), left ventricular end-diastolic volume(LVEDV)and Left ventricular ejection fraction (LVEF) 4 weeks after PCI, and also analyzed the major adverse cardiac events(MACE) and six-minute walk test between the hospitalization period and 6 months after PCI. Results The number of the stenotic vessls in the observation group was greater than in the observation group[(1.9±0.9) vs (1.2±0.8), P<0.05], and the percentage of infarct-related artery in the left anterior descending artery was also higher (62.6% vs 41.2%, P<0.05). The diameters of LVESV, LVEDV were larger, and the LVEF was lower than the control group. The incidence of MACE between the hospitalization period and 6 months after PCI in the observation group was higher, while shorter in the six-minute walk test than the control group. Conclusions The pSO2 during primary PCI with STEMI is a reliable index in evaluating the clinical efficacy and prognostic value.
Miller R D. Anesthesia Vol,Ⅰ[M]. 5 th.ed. New York, Churchill Livingstone, 2001: 1264.
[4]
陈在嘉,高润霖.冠心病[M]. 北京:人民卫生出版社,2002:503.
[5]
ATS committee on proficiency standards for clinical pulmonary function laboratories. ATS statement:guidelines for the six-minute walk test[J]. Am J Respir Crit Care Med, 2012,166:111-117.
Gore J M, Sloank K. Use continous monitoring of mixed venous saturation in the coronary care unite[J] Chest, 1984, 86: 751.
[9]
Steg P G, James S K, Atar D, et al. Guidelines for the management of acute myocardial infraction in patients presenting with ST-segment elevation[J]. Eur Heart J, 2012, 33 (22) : 2569- 2619.
[10]
O’Gara P T, Kushner F G, Ascheim D D, et al. 2013ACCf/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cadiology Foundation/ American Heart Association Task Force on practice guideline [J]. Circulation, 2013, 127(4) : e362-e425.
[11]
Gray B A, Hyde R W, Hodges M, et al. Alterations in lung volume and pulmonation in relation to hemodynamic changes in acute myocardial infarction[J]. Circulation, 1979, 59: 551.
[12]
Puymirat E, Simon T, Steg P G, et al. Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction[J]. JAMA, 2012, 33: 101-108.
[13]
Gunnell A S, Einarsdottir K, Sanfilippo F, et al. Improved long term survival in patients on combination therapies following an incident acute myocardial infraction: a longitudinal population-based study[J]. Heart, 2013, 99: 1353-1358.