Infection of high risk human papillomavirus genotype in cervical epithelium in Beijing
ZHANG Yiping1,TAN Yanping1,SUN Lijuan1, LIANG Baoxia1, WANG Li2
1.Department of Gynecology, The Third Hospital of Beijing Municipal Corps, Chinese People’s Armed Police Force, Beijing 100141, China; 2.Department of Neurosurgery,Kunming Yan’an Hospital, Kunming 650111,China
Abstract：Objective To investigate the infection of high risk human papillomavirus subtype in cervical epithelium in Beijing. Methods From September 2012 to March 2015 ,female outpatients in this hospital received HPV subtype gene testing .The infection rate of 13 kinds of HR-HPV in the crowd and in different age group were observed. Results The total infection rate of HPV was 18.59%(865/4654) in this group, among these the rate of single subtype HPV infection was 74.34%(643/865), the multiple subtype infection accounted for 25.66%(222/865).The total infection rate of HR-HPV was 17.15% (798/4654 ), except 67 cases of single low risk HPV infection.The top six subtypes of HR-HPV in crowd were HPV16(3.59%), HPV52(3.31%), HPV58(3.24%), HPV51(2.41%), HPV39(2.30%), and HPV18(1.78%). Before the age of 20 the infection rate of HR-HPV was the highest(30.05%),and then decreased with the increase of age. The infection rate increased after the age of 40 and during 46-50 a second peak was observed(16.55%), after the age of 50 the lowest infection rate(12.47%) was observed.Conclusion The common HR-HPV subtypes in Beijing region are HPV16, HPV52 and HPV58,and the age distribution manifests two peaks.
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2016, Vol. 27 
