Comparison of clinical effectiveness of treating the abnormal uterine bleeding by using NovaSure and levonorgestrel-releasing intrauterine system
LIU Ping1, GUO Lei2, MA Xuelian2, and FENG Limin2
1.Department of Gynaecology and Obstertrics, Beijing Fengtai Hospital, Beijing 100071, China; 2.. Department of Gynaecology and Obstertrics, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing 100050, China
Abstract：Objective To investigate the clinical effectiveness of treating the abnormal uterine bleeding by using NovaSure and levonorgestrel-releasing intrauterine system.Methods AUB patients who had been admitted to Tiantan Hospital for NovaSure endometrial ablation and levonorgestrel-releasing intrauterine system between December, 2013 and August, 2014 were retrospectively analyzed. There were 36 patients for NovaSure and 42 patients for levonorgestrel-releasing intrauterine system to compare the information about present and one-year after the operation.Results The scores of NovaSure and LNG-IUS one year after the operation were (324.1±139.7)points and (255.8±96.1)points, respectively (P<0.05).The scores of menalgia were (2.94±1.55) points and (3.73±1.95)points, respectively(P<0.05). The one-year amenorrhea rates were 66.6% and 31.0%, respectively (P<0.05). The rates of relieves of menalgia were 59.1% and 89.2%, respectively (P<0.05).Conclusions NovaSure and LNG-IUS to treat AUB are both significantly effective. It is more effective to treat hypermenorrhea and lead to amenorrhea by NovaSure. It is better to relieve menalgia and the rates of that are higher by LNG-IUS.
刘 萍，郭 蕾，马雪莲，冯力民. 诺舒与左炔诺孕酮宫内缓释系统治疗异常子宫出血的疗效比较[J]. 武警医学, 2016, 27(6): 580-582.
LIU Ping, GUO Lei, MA Xuelian, and FENG Limin. Comparison of clinical effectiveness of treating the abnormal uterine bleeding by using NovaSure and levonorgestrel-releasing intrauterine system. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(6): 580-582.
Gkrozou F, Dimakopoulos G, Vrekoussis T, et al. Hysteroscopy in women with abnormal uterine bleeding: a meta-analysis on four major endometrial pathologies [J]. Arch Gynaecol Obstet, 2015, 291(6): 1347-1354.
[2]
Munro M G, Critchley H O D, Broder M S,et al. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age [J]. Int J Gynaecol Obstet, 2011 113(1): 3-13.
[3]
Fakih M, Cherfan V, Abdallah E,et al. Success rate, quality of life, and descriptive analysis after generalized endometrial ablation in an obese population [J]. Int J Gynaecol Obstet, 2011, 113(2): 120-123.
[4]
Flegal K M, Carroll M D, Ogden C L,et al. Prevalence and trends in obesity among US adults, 1999-2008[J]. JAMA, 2010, 303(3): 235-241.
[5]
Marret H, Fauconnier A, Chabbert-Buffet N,et al. Clinical practice guidelines on menorrhagia: management of abnormal uterine bleeding before menopause [J]. Eur J Obstet Gynecol Reprod Biol, 2010, 152(2): 133-137.
Hjermstad M J, Fayers P M, Haugen D F,et al. Studies comparing numerical rating scales, verbal rating scales, and visual analogue scales for assessment of pain intensity in adults: a systematic literature review [J]. J Pain Symptom Manage, 2011, 41(6): 1073-1093.
Choi Y S, Cho S H, Lim K J, et al. Effects of LNG-IUS on nerve growth factor and its receptors expression in patients with adenomyosis [J]. Growth Factors, 2010, 28(6): 452-460.
[13]
Heikinheimo O, Gemzell-Daniellsson K. Emerging indications for the levonorgestrel-releasing intrauterine system (LNG-IUS) [J]. Acta Obstet Gynecol Scand, 2012, 91(1): 3-9.
[14]
Bednarek P H, Jensen J T. Safety, efficacy and patient acceptability of the contraceptive and non-contraceptive uses of the LNG-IUS [J]. Int J Women Health, 2009, 1: 45-58.
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