Abstract：Objective To evaluate the prognostic value of plasma levels of uric acid (UA) in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI) . Methods A total of 400 patients with AMI who underwent primary PCI were divided into high UA group and low UA group on the basis of whether UA exceeded upper quartiles. The Baseline characteristics, laboratory findings, angiographic characteristics and major adverse cardiac events (MACEs) were compared between the two groups. Logistic multivariate regression analysis was used to assess the predictive value for in-hospital MACEs and the Kaplan-Meier method was applied in the MACE free survival rate analysis according to the levels of UA. Results 101 patients reported MACEs during ihospitalization. Multivariate forward stepwise Logistic regression analysis showed that UA>395 μmol/L, Killip class >1, multiple (≥double-vessel CAD) coronary arteries with stenosis and left ventricular ejection fraction <50% were independent predictors of subsequent MACEs. Conclusion The present study has showed that high levels of UA on admission are independently associated with in-hospital cardiovascular events in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention.
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2016, Vol. 27 
