Relationships between oxidative stress, inflammation and ischemic stroke
HE Jufang1, LI Tingting2, SUN Xiaoyun3, DONG Mei1, LI Kang1, BAI Guangliang1, ZHANG Lina1, MEI Xue1, and WANG Ruwei1
1.Department of Clinical Laboratory,the 309th Hospital of PLA, Beijing 100091, China; 2.Grade 10,Medical Laboratory Speiality,Hebei North Medical University,Zhangjiakou 075000,China; 3.Weigongcun Cadre’s Sanatorium Clinic of the Political Department of the Central Military Commision,Beijing 100081,China
Abstract：Objective To investigate the diagnostic value of levels of TAC,Ox-LDL,SOD and Hs-CRP of serum for patients with ischemic stroke.Methods The levels of TAC and Ox-LDL were detected by enzyme-linked immunosorbent assay. A Beckman Coulter AU5821 blood biochemical analyzer was used to detect other indexes.Results In the patient group, the level of TAC was decreased significantly, almost 1/12 of the level of the normal control group(P<0.01),and the levels of HDL-C and SOD were also decreased(P<0.05), but the levels of Hs-CRP, Ox-LDL and LDL-C were markedly increased(P<0.01).In the patient group, the level of Hs-CRP was 16 times that of the normal control group, the level of Ox-LDL was 1.7 times the normal level, and the level of LDL-C was 1.6 times the normal level.Conclusions There is significant difference between ischemic stroke patients and normal controls.The occuurence of ischemic stroke is closely related to oxidative stress and inflammation.
何菊芳, 李婷婷, 孙晓运, 董梅, 李康, 白光亮, 张丽娜, 梅雪, 王汝微. 氧化应激及炎性反应与缺血性脑卒中的关系[J]. 武警医学, 2016, 27(12): 1234-1236.
HE Jufang, LI Tingting, SUN Xiaoyun, DONG Mei, LI Kang, BAI Guangliang, ZHANG Lina, MEI Xue, and WANG Ruwei. Relationships between oxidative stress, inflammation and ischemic stroke. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(12): 1234-1236.
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2016, Vol. 27 
