Difference in cognitive impairment patterns by the Montreal Cognitive Assessment-Basic in patients of different age with mild cognitive impairment
TANG Yu1, HAO Dandan1, QIN Weiting1, WEN Xiao1, LI Fang2
1.Department of Neurology, 2. Department of Gerontology, Fuxing Hospital, the Eighth Clinical Medical College, Capital Medical University, Beijing 100038, China
Abstract:Objective To investigate the difference in the Montreal Cognitive Assessment-Basic(MoCA-B) sub-item scores between patients of different age with mild cognitive impairment(MCI).Methods One hundred and ninety MCI patients were recruited from the outpatients and inpatients of the Department of Neurology and surrounding communities between January 2017 and December 2017. Patients were divided into three groups according to their age: 50-59(n=47), 60-69(n=73) and 70-79(n=70). All the patients were subjected to a survey by means of Mini-Mental State Examination(MMSE)and MoCA-B.Results There was no significant difference between the three groups in gender, levels of education, MMSE or MoCA-B. When each item of MoCA-B was compared between the three groups, verbal fluency test(VFT) and delayed recall were significantly different(P<0.05). Patients under 60 got a little higher scores in VFT than those above 60(0.8±0.5 vs 0.5±0.6), but the difference was not statistically significant. For verbal delayed recall, the scores of the three groups were(1.1±1.0),(0.4±0.8) and(0.5±1.0),respectively. Patients under 60 got higher scores than older ones. The difference was significant between the three groups(P<0.05).Conclusions When interpreting the scores of each item of MoCA-B, we should pay attention to the possible influence of age, especially the verbal delayed recall score.
唐煜, 郝单单, 秦玮婷, 文潇, 李放. 年龄对轻度认知障碍患者蒙特利尔认知评估量表基本版得分的影响[J]. 武警医学, 2019, 30(9): 787-790.
TANG Yu, HAO Dandan, QIN Weiting, WEN Xiao, LI Fang. Difference in cognitive impairment patterns by the Montreal Cognitive Assessment-Basic in patients of different age with mild cognitive impairment. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(9): 787-790.
Ton T G N, DeLeire T, May S G, et al. The financial burden and health care utilization patterns associated with amnestic mild cognitive impairment [J]. Alzheimers Dement, 2017, 13(3):217-224.
[2]
Sheikh F, Ismail Z, Mortby M E, et al. Prevalence of mild behavioral impairment in mildcognitive impairment and subjective cognitive decline, and its association with caregiver burden [J]. Int Psychogeriatr, 2018, 30(2):233-244.
[3]
Petersen R C, Lopez O, Armstrong M J, et al. Practice guideline update summary: mild cognitive impairment: report of the guideline development, dissemination, and implementation subcommittee of the American Academy of neurology[J]. Neurology, 2018, 90 (8):126-135.
[4]
Taragano F E, Allegri R F, Heisecke S L, et al. Risk of conversion to dementia in a mild behavioral impairment group compared to a psychiatric group and to a mild cognitive impairment group[J]. J Alzheimers Dis, 2018, 62(1):227-238.
[5]
Nasreddine ZS, Phillips NA, Bédirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment[J]. J Am Geriatr Soc, 2005, 53(4):695-699.
Julayanont P, Tangwongchai S, Hemrungrojn S, et al. The Montreal Cognitive Assessment-Basic: A Screening Tool for Mild Cognitive Impairment in Illiterate and Low-Educated Elderly Adults[J]. J Am Geriatr Soc, 2015,63(12):2550-2554.
[12]
Chen K L, Xu Y, Chu A Q, et al. Validation of the Chinese version of Montreal cognitive assessment basic for screening mild cognitive impairment[J]. J Am Geriatr Soc, 2016, 64(12): e285-e290.
[13]
Espinosa A, Alegret M, Valero S, et al. A longitudinal follow-up of 550 mild cognitive impairment patients: evidence for large conversion to dementia rates and detection of major risk factors involved[J]. J Alzheimers Dis, 2015, 43(2): 335.
[14]
Di C A, Baldereschi M, Lamassa M, et al. Daily Function as predictor of dementia in cognitive impairment, no dementia (CIND) and mild cognitive impairment (MCI): an 8-year follow-up in the ILSA study[J]. J Alzheimers Dis, 2016, 53(2): 505-515.
Stolwyk R, Bannirchelvam B, Kraan C, et al. The cognitive abilities associated with verbal fluency task performance differ across fluency variants and age groups in healthy young and old adults [J]. J Clin Exp Neuropsychol, 2015, 37(1): 70-83.
Tang E Y, Brayne C, Albanese E, et al. Mild cognitive impairment definitions: more evolution than revolution [J]. Neurodegener Dis Manag, 2015, 5(1): 11-17.