Abstract：Objective To explore the influencing factors of carotid intima-media thickness in continuous ambulatory peritoneal dialysis patients.Methods The continuous ambulatory peritoneal dialysis(CAPD) patients were divided into the increased CIMT group(CIMT≥1.0 mm) and normal CIMT group (CIMT＜1.0 mm) based on their carotid color Doppler ultrasound results. The relationships between serum phosphorous, hs-CRP, IL-6 and the increased CIMT were analyzed in the two groups.Results The proportion of the increased CIMT in CAPD patients was 45.83%. The differences in age, numbers of diabetes mellitus patients, serum phosphorous, hs-CRP, IL-6 and TNF-α between the two groups were statistically significant (P<0.05). Multivariate logistic regression analysis showed that serum phosphorous (P=0.003, OR=1.113), hs-CRP (P=0.001, OR=1.148) and IL-6 (P=0.016, OR=1.056) were significant independent risk factors for the increased CIMT in CAPD patients.Conclusions The thickening of CIMT in CAPD patients is related to serum phosphorous, hs-CRP, IL-6 and other factors, which is an important risk factor for the occurrence of vascular calcification and cardiovascular complications in CAPD patients.
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2019, Vol. 30 
