Drug resistance of pathogens of venous catheter infections in children with extensive burn
LIU Jing1, GAO Wanfeng1, WANG Jian1, HAN Zhongxue1, JIA Shiying1, SONG Lijie2
1. Department of Clinical Laboratory,Liaoning Provincial Corps Hospital,Chinese People's Armed Police Force, Shenyang 110034, China; 2. Department of Clinical Laboratory, the Third Medical Center of Chinese PLA General Hospital,Beijing 100039,China
Abstract：Objective To investigate the pathogens of venous catheter infections in children with large-area burn and analyze their drug resistance. Methods Between January 2014 and January 2019, 478 burn patients were selected from the Burn Department of our hospital and the Third Medical Center of the PLA. All the venous catheters used by these patients were collected for bacterial culture and identification. Results Three hundred and four strains of pathogenic bacteria were isolated from the 478 children with extensive burn. There was significant difference in the infection rate of the femoral vein, internal jugular vein and subclavian vein at the puncture sites of cardiac venous catheters (P<0.05), and in the duration of catheter retention and hospitalization (P<0.05). These strains of pathogenic bacteria included 113 (37.17%) strains of Gram-positive bacteria, 183 (60.20%) strains of Gram-negative bacteria and 8(2.63%) strains of fungi. Drug sensitivity test showed that Staphylococcus aureus was sensitive to vancomycin and linezolid, while Pseudomonas aeruginosa was sensitive to piperacillin/tazobactam and imipenem. Conclusions The younger the children with large-area burn, the higher the infection rate, the higher the infection rate of the femoral vein. The longer their hospital stay, the higher the infection rate.
刘静, 高万峰, 王俭, 韩忠学, 贾世英, 宋丽洁. 大面积烧伤患儿静脉导管感染病原菌情况调查与耐药性分析[J]. 武警医学, 2020, 31(5): 386-388.
LIU Jing, GAO Wanfeng, WANG Jian, HAN Zhongxue, JIA Shiying, SONG Lijie. Drug resistance of pathogens of venous catheter infections in children with extensive burn. Med. J. Chin. Peop. Armed Poli. Forc., 2020, 31(5): 386-388.
2020, Vol. 31 
