超声弹性成像技术评估急性脑梗死颈动脉粥样硬化斑块稳定性

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (694 KB)
输出: BibTeX | EndNote (RIS)

摘要目的探讨应用超声弹性成像技术评估急性脑梗死患者颈动脉粥样硬化斑块稳定性,并进行早期预测。方法选取2016年1-9月医院行颈动脉超声检查的急性脑梗死住院患者60例为急性脑梗死组,另选取门诊非急性脑梗死患者55例为对照组,采集两组患者基线资料,探查并测量颈动脉内膜厚度(intima media thickness,IMT)及斑块回声,采集相关的弹性参数(如弹性评分、弹性面积比值等)的数据并进行统计学分析。结果急性脑梗死组IMT明显厚于对照组(1.71±0.20 vs 1.34±0.27,P<0.05);二维灰阶超声低回声斑块、等回声斑块、混合回声斑块、强回声斑块数量两组之间未出现统计学差异(P>0.05);超声弹性评分低回声斑块和混合回声斑块急性脑梗死组明显低于对照组(1.22±0.43 vs 1.73±0.78,P=0.033;2.95±0.51 vs 3.38±0.59,P=0.036);超声斑块弹性面积比值低回声斑块与混合回声斑块急性脑梗死组明显低于对照组 (1.15±0.09 vs 1.23±0.10,P=0.029;1.44±0.12 vs 1.55±0.09,P=0.010)。结论应用超声弹性成像技术可以区别出颈动脉斑块的稳定性,为急性脑梗死提供预测价值。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	陈旭兰
	吴小伟
	蔡伟

关键词 ：超声检查, 实时超声弹性成像技术, 颈动脉, 粥样硬化斑块, 急性脑梗死

Abstract：Objective To assess the stability of carotid atherosclerosis plaques by ultrasound elastography imaging in order to predict acute cerebral infarction. Methods Sixty in-patients with acute cerebral infarction were enrolled between January and September in 2016 (acute cerebral infarction group), while another 55 out-patients undergoing cervical vascular examination in the Affiliated Hospital of People's Armed Police Logistics University served as the control group. The baseline data of the two groups was collected as well, including BMI, disease history, blood pressure and results of biochemical tests. The carotid intima media thickness (IMT) and plaque echo features were observed using conventional 2D ultrasound methods. The associated elastic parameters (e.g. elastic score, elastic area ratio) were acquired from the plaques' elastic dynamic image information through real-time elastography. Statistical analysis was performed. Results IMT in the acute cerebral infarction group (1.71±0.20) was significantly higher than in the control group (1.34±0.27) (P<0.05). The low echo plaque elastic score and the mixed echo plaque elastic score were both significantly lower in the control group than in the acute cerebral infarction group(1.22±0.43 vs 1.73±0.78,P=0.033;2.95±0.51 vs 3.38±0.59,P=0.036, respectively). The low echo plaque elastic area ratio and mixed echo plaque elastic area ratio were both significantly lower in the acute cerebral infarction group than in the control group (1.15±0.09 vs 1.23±0.10,P=0.029;1.44±0.12 vs 1.55±0.09,P=0.010, respectively). Conclusions The stability of carotid artery plaques can be identified by ultrasound elastography imaging to predict acute cerebral infarction.

Key words： ultrasound examination real-time ultrasound elastography carotid arteries atherosclerosis acute cerebral infarction

收稿日期: 2019-07-10

ZTFLH:

R445.1

通讯作者: 蔡伟,E-mail:weiwei.well@163.com

作者简介: 陈旭兰,硕士,副主任医师。

引用本文:

陈旭兰, 吴小伟, 蔡伟. 超声弹性成像技术评估急性脑梗死颈动脉粥样硬化斑块稳定性[J]. 武警医学, 2020, 31(5): 426-429. CHEN Xulan, WU Xiaowei, CAI Wei. Real-time ultrasound elastography in evaluating carotid atherosclerosis plaques. Med. J. Chin. Peop. Armed Poli. Forc., 2020, 31(5): 426-429.

链接本文:

http://journal08.magtechjournal.com/Jwk_wjyx/CN/ 或 http://journal08.magtechjournal.com/Jwk_wjyx/CN/Y2020/V31/I5/426

[1]	Huang C, He Q, Huang M, et al. Non-invasive identification of vulnerable atherosclerotic plaques using texture analysis in ultrasound carotid elastography: an in vivo feasibility study validated by magnetic resonance imaging[J]. Ultrasound Med Biol, 2017, 43(4):817-830.
[2]	Naim C, Douziech M, Therasse E, et al. Vulnerable atherosclerotic carotid plaque evaluation by ultrasound, computed tomography angiography, and magnetic resonance imaging: an overview[J]. Can Assoc Radiol J, 2014, 65(3):275-286.
[3]	Mosleh W, Adib K, Natdanai P, et al. High-risk carotid plaques identified by CT-angiogram can predict acute myocardial infarction[J]. Int J Cardiovasc Imaging,2017,33(4):561-568.
[4]	智光,穆洋.超声技术对颈动脉斑块的评价[J].武警医学,2013, 24(9):737-740.
[5]	Li R,Duncan B B,Metcalf P A,et al.Bmode-detected carotid artery plaque in a general population[J]. Stroke, 1994, 25(12):2377-2383.
[6]	Ophir J, Cespedes I, Ponnekanti H, et al. Elastography: a quantitative method for imaging the elasticity of biological tissues[J]. Ultrason Imaging, 1991,13(2):111-134.
[7]	Hwang D S, Shin E S, Kim S J, et al. Early differential changes incoronary plaque composition according to plaque stability following statininitiation in acute coronary syndrome classification and analysis byintravascular ultrasound-virtual histology[J]. Yonsei Med J, 2013, 54(2):336-344.
[8]	罗艳红,陈怡,马红英,等. 实时超声弹性成像技术结合声学密度定量技术对颈动脉斑块稳定性的研究[J]. 中国超声医学杂志, 2018, 34(3):197-200.
[9]	沈玥,蔡爱露. 超声弹性成像技术在颈动脉粥样硬化斑块中的应用进展[J]. 医学综述, 2018, 24(17):197-200.
[10]	Sigrist R S, Liau J, Kaffas A E, et al. Ultrasound elastography: review of techniques and clinical applications[J]. Theranostics, 2017, 7(5):1303-1329.
[11]	姚俊东,张周龙,王运昌.声脉冲辐射力弹性成像联合超声造影评价颈动脉不稳定斑块及对急性脑缺血性事件的预测[J].中国医学影像学杂志, 2018,26(5):365-368 .
[12]	黄书晖,陈廷财,陈漫清,等.超声弹性成像技术评估颈动脉斑块稳定性与青中年脑卒中的关系分析[J].中国现代药物应用, 2019, 13(3):11-13.
[13]	胡小丽,车正兰. 超声弹性成像在颈动脉斑块中的诊断价值[J].临床超声医学杂志, 2015,17(3):215-216.
[14]	林长江,朱建平,孙立. 实时组织弹性技术评估颈动脉斑块性质的应用研究[J]. 功能与分子医学影像学(电子版), 2016,5(2):906-1011.
[15]	陈旭兰,钱伟.颈动脉粥样硬化斑块超声弹性成像技术及其评估研究进展[J].武警医学, 2019, 30(5):369-372.
[16]	Naim C, Cloutier G, Mercure E, et al. Characterisation of carotid plaques with ultrasound elastography: feasibility and correlation with high-resolution magnetic resonance imaging[J]. Eur Radiol, 2013, 23(7):2030-2041.
[17]	Cloutier G, Cardinal M R, Ju Y, et al. Carotid plaque vulnerability assessment using ultrasound elastography and echogenicity analysis[J]. AJR Am J Roentgenol, 2018, 211(4):847-855.