Abstract：Objective To analyze the risk factors for coronary artery perforation during percutaneous coronary intervention. Methods The clinical data on patients treated with percutaneous coronary intervention in the Department of Cardiology of Chinese PLA General Hospital between January 2011 and September 2020 was consecutively collected. These patients were grouped according to the occurrence of coronary perforation. Multivariate logistic regression analysis was used to analyze risk factors for complications with coronary perforation during percutaneous coronary intervention. Results A total 57 580 patients were enrolled in the final statistical analysis, 90 cases of whom were complicated with coronary perforation. Multivariate logistic regression analysis showed that age above 70(OR=2.69, 95% CI:2.25-3.13), femininity(OR=1.46, 95% CI:1.05-1.87), diabetic history(OR=3.05, 95% CI:2.11-3.99), type C lesions(OR=3.69, 95% CI:3.02-4.36), complete occlusion lesions(OR=4.52,95% CI:3.88-5.16), calcification(OR=1.52, 95% CI:1.17-1.87), hydrophilic guide wire and rotablation (OR=10.4, 95% CI:8.87-11.93) were correlated with the incidence of coronary perforation. Conclusions Age above 70, femininity, a history of diabetes mellitus, type C lesions, complete occlusion lesions, calcification, hydrophilic guide wire and rotablation are independent risk factors for the incidence of coronary perforation in patients under percutaneous coronary intervention.
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