1. Department of Military Health Statistics, Naval Medical University, Shanghai 200433, China; 2. Department of Rehabilitation, Children's Hospital of Fudan University, Shanghai 201102, China
Abstract：Objective To explore the relationships between bile duct stent placement and post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in children.Methods Based on pediatric patients in the National Inpatient Sample (NIS) database of the United States, logistic regression accounting was used for survey design while multiple imputation was adopted to study the relationships between biliary stent placement and PEP. Subgroup analysis was conducted according to gender.Results Children with biliary stent placement were at higher risk of PEP than those without (OR: 1.44, 95% CI: 1.05-1.99, P=0.0246). The results of subgroup analysis showed that boys with biliary stent placement were about 1.9 times as vulnerable to PEP as those without (OR: 1.89, 95% CI: 1.08-3.31, P=0.0262), but for female pediatric patients, bile duct stent placement was not found to be associated with PEP.Conclusions Bile duct stent placement is associated with an increased risk of PEP in children. Therefore, when placing bile duct stents in children, clinicians should take preventive measures, discontinue surgery or change surgical approaches to reduce the risk of PEP.
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2022, Vol. 33 
