Effect and safety of pulmonary protective ventilation combined with intravenous inhalational anesthesia in children treated with electronic cochlear implantation
ZENG Ruxiao, TIAN Ye, LIU Xiaomei
Department of Anesthesiology,the Sixth Medical Center of Chinese PLA General Hospital, Beijing 100048, China
Objective To study the effect and safety of pulmonary protective ventilation combined with intravenous inhalational anesthesia in pediatric electronic cochlear (CI) implantation.Methods Eighty children with severe or very severe sensorineural hearing loss (SNHL) who received CI implantation in the Sixth Medical Center of Chinese PLA General Hospital from October 2019 to October 2021 were selected as the research objects, and they were divided into the control group and the observation group by random number table method, with 40 cases in each group. Both groups were given intravenous inhalation combined anesthesia, the control group with conventional ventilation strategy and the observation group with lung protective ventilation strategy. The hemodynamic indexes before (T0) and 30 min after (T1) the ventilation strategy and the adverse reactions after anesthesia were compared between the two groups.Results At T0, there were no significant differences in HR, MAP and SPO2 between the two groups. At T1, HR, MAP and SPO2 in the two groups decreased, and the indexes of the observation group was lower than those of the control group (P<0.05). After treatment, MDA level [(6.21±0.19) μmol/L] in the observation group was significantly lower than that in the control group. SOD level [(90.77±11.54) U/L] was significantly higher than that of control group (P<0.05). The rate of the adverse reactions in the observation group (7.50%) was lower than that in the control group (27.50%)(P<0.05).Conclusions Pulmonary protective ventilation combined with intravenous inhalation anesthesia is safe and reliable, which can maintain hemodynamic stability during CI implantation in children, reduce patients’ stress response, and reduce the occurrence of adverse reactions after anesthesia recovery.
曾如筱, 田冶, 刘晓梅. 肺保护性通气配合静吸复合麻醉在小儿电子耳蜗植入术中的应用效果及安全性[J]. 武警医学, 2022, 33(9): 742-744.
ZENG Ruxiao, TIAN Ye, LIU Xiaomei. Effect and safety of pulmonary protective ventilation combined with intravenous inhalational anesthesia in children treated with electronic cochlear implantation. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(9): 742-744.
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