Abstract：Objective To evaluate the effect of goal-directed intraoperative fluid therapy guided by stroke volume variation (SVV) on adult patients who underwent abdominal surgery. Methods Patients undergoing abdominal surgery with arterial puncture placement intraoperatively from January 2016 to September 2021 in Characteristic Medical Center of PLA Rocket Force were selected and divided into goal-directed fluid therapy (GDFT) group and conventional fluid infusion (CFI) group according to SVV monitoring. The length of hospital ICU stay, length of hospital stay, 30-d mortality, postoperative nausea and vomiting (PONV), hypotension, tachycardia and the amount of intraoperative fluid transfusion and blood transfusion were recorded. Results A total of 1055 patients were included, with 713 patients in the GDFT group and 342 patients in the CFI group. The amount of intraoperative fluid transfusion in CFI group [(1611.26±828.40) ml] was more than GDFT group [(1497.35±730.73) ml], which was statistically significant (P<0.05). The length of ICU stay in the GDFT group was (1.93±3.77) d, the hospital stay was (30.20±17.40) d, the incidence of 30-d mortality was 4.35% and the incidence of PONV was 20.90%, while the data for the CFI group were respectively (1.95±4.12) d, (30.26±19.20) d, 5.26% and t 25.73%, and there was no statistical difference between the two groups. Conclusions Goal-directed fluid therapy with SVV monitoring has no effect on the outcome of patients undergoing abdominal surgery.
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