Abstract：Objective To observe the clinical efficacy of acupuncture combined with traditional Chinese medicine (TCM) based on syndrome differentiation on patients with primary subjective tinnitus. Methods A non-randomized controlled trial design was performed. Patients with primary subjective tinnitus who met the criteria were included and divided into the acupuncture combined with TCM group and the acupuncture alone group according to their intervention. The acupuncture alone group was treated with acupuncture alone, and the acupuncture combined with TCM group was treated with TCM based on syndrome differentiation on the basis of the above acupuncture treatment. Treatment lasted for 4 weeks. Tinnitus Evaluation Questionnaire (TEQ) was completed before treatment, 4 weeks after treatment and 3 months after the end of treatment to score efficacy and recurrence, and the difference in efficacy and recurrence rate between the two groups was compared. Results There were 55 analyzable cases in the acupuncture combined with TCM group and 43 cases in the acupuncture alone group. There were significant differences in gender, age and course of disease between two groups (P<0.05). After the propensity score matching method, 38 patients in each group reached to the matching tolerance, thus ensuring the comparability of baseline between two groups. After 4 weeks of treatment, the TEQ score of acupuncture combined with TCM group was significantly lower than that of acupuncture alone group (P<0.05), and the total effective rate of acupuncture combined with TCM group was 89.47%, which significantly higher than that of acupuncture alone group (71.05%) (P<0.05). At the three months’ follow-up after the end of treatment, the recurrence rate of acupuncture combined with TCM group (5.88%) was significantly lower than that of acupuncture alone (18.52%) (P<0.05). Conclusions The efficacy of acupuncture combined with TCM group based on syndrome differentiation on primary subjective tinnitus is better than that of acupuncture alone.
邢庆昌, 王卫卫, 胡文慧. 针刺与中医药物结合辨证治疗特发性主观性耳鸣的疗效[J]. 武警医学, 2022, 33(11): 938-940.
XING Qingchang, WANG Weiwei, HU Wenhui. Study on treatment of primary subjective tinnitus with acupuncture combined with traditional Chinese medicine based on syndrome differentiation. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(11): 938-940.
Wu D, Ham D, Rosedale R. Physiotherapy assessment and treatment of chronic subjective tinnitus using mechanical diagnosis and therapy: a case report[J]. J Man Manip Ther,2020,28(2):119-126.
Sruthi N, Venkataramanujam N C, Karthikeyan P, et al. A comparative study of treatment outcomes of music therapy, tinnitus maskers and pharmacotherpy in chronic subjective tinnitus[J]. Indian J Otolaryngol, 2021, 74 (2): 185-189.
[12]
Baykara M, Sagiroglu S. An evaluation of magnetic resonance imaging with histogram analysis in patients with idiopathic subjective tinnitus[J]. North Clin Istanb,2018,6(1):59-63.
Koning H M. Proprioception: the missing link in the pathogenesis of tinnitus?[J]. Int Tinnitus J,2021,24(2):102-107.
[15]
Han, Q, Zhang, Y, Liu, D, et al. Disrupted local neural activity and functional connectivity in subjective tinnitus patients: evidence from resting-state fMRI study[J]. Neuroradiology,2018,60(11):1193-1201.
2022, Vol. 33 
