Clinical efficacy of compound Huangbai liquid after sacrococcygeal pilonidal sinus resection
LI Zhuang1,2, DONG Xiangyu2, PENG Xue3, WANG Qiqi4, SUN Yanjun2, SUN Dengqun2
1. The First Clinical Medical of Anhui University of Chinese Medicine, Hefei 230038, China; 2. Department of General Surgery, 3. Department of Pathology, 4. Clinical Laboratory, Anhui Provincial Corps Hospital of Chinese People's Armed Police Force, Hefei 230041, China
摘要目的 观察骶尾部藏毛窦切除术术后应用复方黄柏液的临床疗效。方法 回顾性分析2016-01至2021-06在武警安徽总队医院进行骶尾部藏毛窦治疗的38例武警战士的临床资料。根据术后是否采用复方黄柏液换药治疗分为观察组和对照组(外科常规治疗),每组19例。比较两组临床疗效、炎性指标、疼痛视觉模拟量表(VAS)、创面愈合时间等指标。结果 观察组患者创面愈合时间[(26.11±12.60)d]、住院时长[(22.68±16.32)d]明显短于对照组[(38.79±21.09)d、(34.32±24.50)d],观察组治疗后VAS评分[(1.11±0.80)分]低于对照组[(1.95±0.91)分],差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组(94.74% vs. 68.42%),差异有统计学意义(P=0.036)。随访3个月两组均无复发,6个月各有1例复发,在12个月对照组复发率高于观察组(10.53% vs. 0),差异无统计学意义(P=0.146)。结论 完成藏毛窦切除手术后的患者,配合复方黄柏液换药治疗疗效显著,可以缓解官兵骶尾部活动疼痛,提高生活质量。
Abstract:Objective To examine the clinical efficacy of the use of compound Huangbai liquid after sacrococcygeal pilonidal sinus resection.Methods The clinical data of 38 officers and soldiers who were treated with sacrococcygeal pilonidal sinus in Anhui Provincial Corps Hospital from January 2016 to June 2021 were analyzed retrospectively. According to the use of compound Huangbai liquid after operation, the subjects were divided into observation group and control group(routine surgical care), with 19 cases in each group. Comparison was made between the different groups in clinical efficacy, the inflammatory index, the visual analogue scale, wound healing time and other indicators during the observation period in both groups.Results The wound healing time and hospital stay in the observation group [(26.11±12.60)and(22.68±16.32)d] were significantly shorter than those in the control group[(38.79±21.09)d and(34.32±24.50)d]. After treatment, the VAS score of the observation group [(1.11±0.80) points] was lower than that of the control group [(1.95±0.91) points], and the difference was statistically significant (P<0.05). The total effective rate of the observation group was higher than that of the control group (94.74% vs. 68.42%), and the difference was statistically significant (P=0.036). There was no recurrence in the follow-up for 3 months, and 1 case recurred in the two groups at 6 months. The recurrence rate in the control group was higher than that in the observation group(10.53% vs. 0)at 12 months, with no statistically significant difference(P=0.146).Conclusions Compound Huangbai liquid therapy is significantly effective, which can relieve the pain of sacral activity and improve the quality of the life of officers and soldiers.
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