Observation on curative effect of cognitive therapy combined with physical exercise in patients with mild cognitive impairment
ZHANG Wei1, LI Xinyu2, LI Haitao1, ZHANG Xiao1, GUO Fang1
1. Department of Neurology, 2. Department of Physical Medicine and Rehabilitation, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050, China
Abstract：Objective To explore the clinical efficacy of combined intervention of exercise and cognition in patients with mild cognitive impairment (MCI). Methods A total of 63 patients with MCI were randomly divided into a study group (n=31) and a control group (n=32). Both groups received general treatment, and the study group received combined training of exercise and cognition for 12 weeks. The Montreal Cognitive Assessment Scale (MoCA) was assessed before and after the training and 12 weeks after the training was stopped. Results There was no statistical difference in MoCA scores between the two groups before treatment. After the end of combined cognitive motor training and 12 weeks after stopping training, the MoCA scores of the study group were higher than those of the control group, with statistical significance (P<0.05). The improvement of cognitive function in the study group was mainly manifested in visuospatial/executive function, attention, language and memory. Conclusions Combined intervention of exercise and cognition can improve the cognitive function of patients with MCI, and has a certain lasting effect.
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2025, Vol. 36 
