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| Clinical analysis of candidal pneumonia in liver failure patients |
| SUN lijian1,2, LIN Fang2，SU Haibin2，LI Lei2, ZHAO Hong2，and WANG Huifen2. |
1. 100853 北京，解放军军医进修学院研究生队；2.100039 北京，解放军第302医院重症监护中心
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Abstract Objective To investigate the clinical features and risk factors of candidal pneumonia in liver failure patients. Methods 150 hospitalized patients with candidal pneumonia from January 1986 to December 2007were analysed retrospectively. Results Broad-spectrum antibiotics were used in 90.0% of the patients and corticosteroids 47. 3% of the patients. 73% of the patients had only lung fungal infection. The main species of Candida was Candida albicans (66%) and Candida tropicalis (16%). Fever (70%) cough and expectoration(85.3%) were the most common clinical features. Leucocytosis was found in 50% of the patients and neutrophil increased in 46.7%. Better effect was achieved when the anti-fungal therapy was initiated earlier or along with long-term therapy regimen (≥2 weeks). Conclusions Most Candidal pneumonia patients with liver failure are given broad-spectrum antibiotics. Candida albicans is popularly used. Fever, cough and expectoration are the most common clinical features. Better outcomes come with early use and sufficient duration of antibiotics.
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Received: 24 January 2012
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