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| Prognostic study of visceral pleural invasion in T2 non-small cell lung cancer |
| ZHANG Jinming1 and WANG Xiaoxin2. 1. Beijing Miyun Teaching Hospital,Capital Medical University,Beijing 101500,China；2. Department of Thoracic Surgery,First Hospital of Peking University,Beijing 100034,China |
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Abstract Objective To assess the relationship between visceral pleural invasion (VPI) in T2 non-small cell lung cancer (NSCLC) and other clinicopathologic characteristics and to evaluate its significance as a prognostic factor. Methods 628 patients with T2 NSCLC underwent curative surgical resection in Miyun County Hospital and the First Hospital of Beijing University. The subjects included 265 patients with stage IB non-small cell lung cancer (T2N0M0) , 223 with stage IIB (T2N1M0), and 140 with stage ⅢA (T2N2M0). The patients were divided into two groups according to the VPI status (group Ⅰ without invation, group Ⅱ with invasion). Both groups were compared in tumor size, histology, associated lymph node involvement, and survival rates. Results VPI (group Ⅱ) was identified in 136 patients (21.7%) and was present in 70 patients with a tumor 3 cm or less and in 66 of patients with a tumor larger than 3 cm in size. 5- and 10-year survival rates were 53.7% and 40.0% in group Ⅰ, and 25.7% and 11.0% in group Ⅱ, respectively (P
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Received: 12 April 2012
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2012, Vol. 23 
